Low blood pressure in Down's syndrome - A link with Alzheimer's disease?

RA Morrison, A McGrath, G Davidson, JJ Brown, GD Murray, AF Lever

Research output: Contribution to journalArticlepeer-review

Abstract

Low blood pressure is reported in Down's syndrome (DS). To assess this and determine whether low pressure results from the disease or from long-term residence in hospital, we measured blood pressure with a random-zero sphygmomanometer in three groups of patients: 52 DS inpatients, 62 DS outpatients, and 60 outpatients with other forms of mental handicap. Relative to normal reference populations, blood pressure was low in both DS inpatients (systolic, score -33 mmHg, P

Original languageEnglish
Pages (from-to)569-575
Number of pages7
JournalHypertension
Volume28
Issue number4
Publication statusPublished - Oct 1996

Keywords

  • hypotension
  • Down's syndrome
  • Alzheimer's disease
  • amyloid beta-protein
  • sympathetic nervous system
  • RANDOM ZERO SPHYGMOMANOMETER
  • DEMENTIA
  • WOMEN
  • AGE
  • HOMOCYSTEINE
  • PRECURSOR
  • PERFUSION
  • FLOW
  • MEN
  • NEUROPATHOLOGY

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