Lower Gastrointestinal Tract

Piper M. Treuting, Mark Arends, Suzanne M Dintzis

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract / Description of output

The large intestine begins at the cecum and includes the appendix (humans only), colon, rectum, and anus. The primary function of the large intestine in all three species is to dehydrate and store fecal material. Extensive reabsorption of water and salt occurs in the right/proximal colon and continues throughout. Movement of the increasingly solid colonic contents from proximal to distal is supported by abundant mucus-secreting goblet cells that serve to lubricate and protect the colonic mucosa from trauma. All three species have abundant bacterial flora within the colon, which carry out a rumen-like function that is more prominent in rodents. Commensal protozoa are frequently present in rodent intestines.
Original languageEnglish
Title of host publicationComparative Anatomy and Histology: a Mouse, Rat and Human Atlas
EditorsPiper M. Treuting, Suzanne M. Dintzis, Kathleen S. Montine
PublisherElsevier Science
Pages213-228
Edition2
ISBN (Print)978-0-12-802900-8
Publication statusPublished - 22 Sept 2017

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