TY - JOUR
T1 - Lower Respiratory Tract Infection: An Unrecognised Risk Factor for High Altitude Pulmonary Oedema?
AU - Humphries, Christopher
PY - 2017/4/27
Y1 - 2017/4/27
N2 - The case of a 25-year-old expedition doctor who developed high altitude pulmonary oedema (HAPE) while climbing in the Swiss Alps is presented, with reference to the literature. The patient's symptoms of HAPE were typical. Less typical was the fact that the doctor had previously been to similar altitudes uneventfully. The only differentiator is that on this expedition he developed a mild lower respiratory tract infection (LRTI) 2 days prior to travel. There has been limited, conflicting evidence regarding LRTI as a risk factor for HAPE and high quality research has not focused on this area. LRTI is not commonly recognised as being a risk in high altitude environments, which may be resulting in lethal consequences. This report aims to inform, provide a clinical question for future high altitude research expeditions, and encourage consideration by expedition and high altitude doctors.Learning pointsLower respiratory tract infection (LRTI) may be a significant risk factor in the development of high altitude pulmonary oedema (HAPE).The diagnosis of HAPE is clinical as investigations have been shown to be unreliable.The Lake Louise HAPE criteria provide a reasonable identification framework but may miss the early stages.
AB - The case of a 25-year-old expedition doctor who developed high altitude pulmonary oedema (HAPE) while climbing in the Swiss Alps is presented, with reference to the literature. The patient's symptoms of HAPE were typical. Less typical was the fact that the doctor had previously been to similar altitudes uneventfully. The only differentiator is that on this expedition he developed a mild lower respiratory tract infection (LRTI) 2 days prior to travel. There has been limited, conflicting evidence regarding LRTI as a risk factor for HAPE and high quality research has not focused on this area. LRTI is not commonly recognised as being a risk in high altitude environments, which may be resulting in lethal consequences. This report aims to inform, provide a clinical question for future high altitude research expeditions, and encourage consideration by expedition and high altitude doctors.Learning pointsLower respiratory tract infection (LRTI) may be a significant risk factor in the development of high altitude pulmonary oedema (HAPE).The diagnosis of HAPE is clinical as investigations have been shown to be unreliable.The Lake Louise HAPE criteria provide a reasonable identification framework but may miss the early stages.
UR - https://europepmc.org/articles/PMC6346869
U2 - 10.12890/2017_000539
DO - 10.12890/2017_000539
M3 - Article
C2 - 30755928
VL - 4
JO - European Journal of Case Reports in Internal Medicine
JF - European Journal of Case Reports in Internal Medicine
IS - 3
ER -