Lung compliance, lung volume and transfer factor for carbon monoxide in anaesthetised sheep: normal values and reproducibility of measurements

D D Collie, N J Watt, P M Warren, I Begara, L Luján

Research output: Contribution to journalArticlepeer-review

Abstract

Measurements of quasistatic compliance (Cqst), effective alveolar volume (VA,eff) and single-breath transfer factor for carbon monoxide (TL,CO, 'sb') were completed in 16 normal, anaesthetised, adult Texel ewes. Regression equations were computed for these variables as a function of bodyweight and the optimal equations selected. The 95 per cent prediction intervals for the equations were calculated such that normal lung function in similar sheep could be accurately predicted. The long term reproducibility of these measurements was assessed in nine sheep, measured at monthly intervals over a period of five months. Although measurements made in individual sheep were often highly variable, the variation between repeated measurements on the separate days for the group was insignificant.
Original languageEnglish
Pages (from-to)137-43
Number of pages7
JournalResearch in Veterinary Science
Volume55
Issue number2
Publication statusPublished - Sep 1993

Keywords

  • Animals
  • Sheep
  • Anesthesia, General
  • Carbon Monoxide
  • Pulmonary Alveoli
  • Lung Volume Measurements
  • Female
  • Lung Compliance

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