LuxS affects flagellar phase variation independently of quorum sensing in Salmonella enterica serovar typhimurium

M H Karavolos, D M Bulmer, K Winzer, M Wilson, P Mastroeni, P Williams, C M A Khan

Research output: Contribution to journalArticlepeer-review

Abstract

LuxS catalyzes the synthesis of the quorum-sensing signaling molecule autoinducer 2. We show that in Salmonella enterica serovar Typhimurium, deletion of the luxS gene polarizes flagellar phase variation toward the more immunogenic phase 1 flagellin. This phenotype is complementable by luxS in trans but is independent of quorum-sensing signals.
Original languageEnglish
Pages (from-to)769-71
Number of pages3
JournalJournal of Bacteriology
Volume190
Issue number2
DOIs
Publication statusPublished - Jan 2008

Keywords

  • Bacterial Proteins
  • Carbon-Sulfur Lyases
  • Flagella
  • Flagellin
  • Gene Deletion
  • Genetic Complementation Test
  • Quorum Sensing
  • Salmonella typhimurium

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