Lymphocyte traffic through antigen-stimulated lymph nodes: I. Complement activation within lymph nodes initiates cell shutdown

I. McConnell, John Hopkins

Research output: Contribution to journalArticlepeer-review

Abstract

Complement activation within lymph nodes has been shown to alter lymphocyte traffic through the node. Challenge of cannulated sheep lymph nodes with either immune complexes or complement activators was found to initiate the phenomenon of cell shutdown associated with antigenic challenge of lymph nodes in primed animals.
Original languageEnglish
Pages (from-to)217-23
Number of pages7
JournalImmunology
Volume42
Issue number2
Publication statusPublished - Feb 1981

Keywords

  • Animals
  • Antibody Formation
  • Antigen-Antibody Complex/immunology
  • Antigens, Viral/immunology
  • Complement Activation
  • Complement C3-C5 Convertases/analysis
  • Lymph Nodes/immunology
  • Lymphocytes/immunology
  • Receptors, Antigen, B-Cell/analysis
  • Sheep
  • T-Phages/immunology
  • Time Factors
  • Tuberculin/immunology

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