Lymphocyte traffic through antigen-stimulated lymph nodes: I. Complement activation within lymph nodes initiates cell shutdown

I. McConnell; John Hopkins

Lymphocyte traffic through antigen-stimulated lymph nodes: I. Complement activation within lymph nodes initiates cell shutdown

Royal (Dick) School of Veterinary Studies

Research output: Contribution to journal › Article › peer-review

Abstract

Complement activation within lymph nodes has been shown to alter lymphocyte traffic through the node. Challenge of cannulated sheep lymph nodes with either immune complexes or complement activators was found to initiate the phenomenon of cell shutdown associated with antigenic challenge of lymph nodes in primed animals.

Original language	English
Pages (from-to)	217-23
Number of pages	7
Journal	Immunology
Volume	42
Issue number	2
Publication status	Published - Feb 1981

Keywords

Animals
Antibody Formation
Antigen-Antibody Complex/immunology
Antigens, Viral/immunology
Complement Activation
Complement C3-C5 Convertases/analysis
Lymph Nodes/immunology
Lymphocytes/immunology
Receptors, Antigen, B-Cell/analysis
Sheep
T-Phages/immunology
Time Factors
Tuberculin/immunology

Access to Document

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1458074/pdf/immunology00243-0042.pdf

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@article{74542da5cacc49a880ac7b740cba2643,

title = "Lymphocyte traffic through antigen-stimulated lymph nodes: I. Complement activation within lymph nodes initiates cell shutdown",

abstract = "Complement activation within lymph nodes has been shown to alter lymphocyte traffic through the node. Challenge of cannulated sheep lymph nodes with either immune complexes or complement activators was found to initiate the phenomenon of cell shutdown associated with antigenic challenge of lymph nodes in primed animals.",

keywords = "Animals, Antibody Formation, Antigen-Antibody Complex/immunology, Antigens, Viral/immunology, Complement Activation, Complement C3-C5 Convertases/analysis, Lymph Nodes/immunology, Lymphocytes/immunology, Receptors, Antigen, B-Cell/analysis, Sheep, T-Phages/immunology, Time Factors, Tuberculin/immunology",

author = "I. McConnell and John Hopkins",

year = "1981",

month = feb,

language = "English",

volume = "42",

pages = "217--23",

journal = "Immunology",

issn = "0019-2805",

publisher = "Wiley-Blackwell",

number = "2",

}

TY - JOUR

T1 - Lymphocyte traffic through antigen-stimulated lymph nodes

T2 - I. Complement activation within lymph nodes initiates cell shutdown

AU - McConnell, I.

AU - Hopkins, John

PY - 1981/2

Y1 - 1981/2

N2 - Complement activation within lymph nodes has been shown to alter lymphocyte traffic through the node. Challenge of cannulated sheep lymph nodes with either immune complexes or complement activators was found to initiate the phenomenon of cell shutdown associated with antigenic challenge of lymph nodes in primed animals.

AB - Complement activation within lymph nodes has been shown to alter lymphocyte traffic through the node. Challenge of cannulated sheep lymph nodes with either immune complexes or complement activators was found to initiate the phenomenon of cell shutdown associated with antigenic challenge of lymph nodes in primed animals.

KW - Animals

KW - Antibody Formation

KW - Antigen-Antibody Complex/immunology

KW - Antigens, Viral/immunology

KW - Complement Activation

KW - Complement C3-C5 Convertases/analysis

KW - Lymph Nodes/immunology

KW - Lymphocytes/immunology

KW - Receptors, Antigen, B-Cell/analysis

KW - Sheep

KW - T-Phages/immunology

KW - Time Factors

KW - Tuberculin/immunology

M3 - Article

VL - 42

SP - 217

EP - 223

JO - Immunology

JF - Immunology

SN - 0019-2805

IS - 2

ER -