Lymphoid hyperplasia and lymphoma in transgenic mice expressing the small non-coding RNA, EBER1 of Epstein-Barr virus

Claire E Repellin, Penelope M Tsimbouri, Adrian W Philbey, Joanna B Wilson

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Non-coding RNAs have critical functions in diverse biological processes, particularly in gene regulation. Viruses, like their host cells, employ such functional RNAs and the human cancer associated Epstein-Barr virus (EBV) is no exception. Nearly all EBV associated tumours express the EBV small, non-coding RNAs (EBERs) 1 and 2, however their role in viral pathogenesis remains largely obscure.
Original languageEnglish
Article numbere9092
JournalPLoS ONE
Volume5
Issue number2
DOIs
Publication statusPublished - 2010

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