Macrophage therapy for murine liver fibrosis recruits host effector cells improving fibrosis, regeneration, and function

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  Autologous macrophage therapy promotes stem cell-mediated liver regeneration: a novel therapy for end-stage liver disease

  Forbes, S. (Principal Investigator) & Iredale, J. (Co-investigator)

  MRC

  1/02/11 → 30/09/14

  Project: Research

  • Macrophage 100%
  • Cell Fate 64%
  • Progenitor Cell 64%
  • Hepatocyte 58%
  • Cholangiocyte 45%

• Csf1 and the control of postnatal growth and organ development in the rat

  Hume, D. (Principal Investigator), Burdon, T. (Co-investigator), Farquharson, C. (Co-investigator) & Whitelaw, B. (Co-investigator)

  MRC

  12/07/10 → 11/06/14

  Project: Research

  • Macrophage 100%
  • Cerebrospinal Fluid 42%
  • Promoter Region 33%
  • Myeloid 31%
  • Dendritic Cell 26%

• The role of Elastin degradation in the pathogenes of liver fibrosis

  Iredale, J. (Principal Investigator) & Forbes, S. (Co-investigator)

  MRC

  1/02/07 → 31/01/12

  Project: Research

  • Liver Fibrosis 100%
  • Fibrosis 72%
  • Myofibroblast 67%
  • Macrophage 59%
  • Inflammation 40%