MAGNETIC-RESONANCE RELAXATION-TIME MAPPING IN MULTIPLE-SCLEROSIS - NORMAL APPEARING WHITE-MATTER AND THE INVISIBLE LESION LOAD

S BARBOSA; LD BLUMHARDT; N ROBERTS; T LOCK; RHT EDWARDS

MAGNETIC-RESONANCE RELAXATION-TIME MAPPING IN MULTIPLE-SCLEROSIS - NORMAL APPEARING WHITE-MATTER AND THE INVISIBLE LESION LOAD

S BARBOSA, LD BLUMHARDT, N ROBERTS, T LOCK, RHT EDWARDS

Research output: Contribution to journal › Article › peer-review

Abstract

Prolonged T-1 and/or T-2 relaxation times (RT) in the normal appearing white matter (NAWM) of patients with multiple sclerosis (MS) have been attributed either to a diffuse abnormality, or to ''small lesions'' undetected by visual inspection of conventional MR images. In a comparison of brain slices from five MS patients and five healthy control subjects, we have confirmed that the average T-1 and T-2 RTs obtained from NAWM in patients with MS are significantly prolonged (p

Original language	English
Pages (from-to)	33-42
Number of pages	10
Journal	Magnetic Resonance Imaging
Volume	12
Issue number	1
Publication status	Published - 1994

Keywords

MRI
MULTIPLE SCLEROSIS
NORMAL APPEARING WHITE MATTER
T-1 AND T-2 RELAXATION TIME
PIXEL MAPPING

Cite this

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title = "MAGNETIC-RESONANCE RELAXATION-TIME MAPPING IN MULTIPLE-SCLEROSIS - NORMAL APPEARING WHITE-MATTER AND THE INVISIBLE LESION LOAD",

abstract = "Prolonged T-1 and/or T-2 relaxation times (RT) in the normal appearing white matter (NAWM) of patients with multiple sclerosis (MS) have been attributed either to a diffuse abnormality, or to ''small lesions'' undetected by visual inspection of conventional MR images. In a comparison of brain slices from five MS patients and five healthy control subjects, we have confirmed that the average T-1 and T-2 RTs obtained from NAWM in patients with MS are significantly prolonged (p",

keywords = "MRI, MULTIPLE SCLEROSIS, NORMAL APPEARING WHITE MATTER, T-1 AND T-2 RELAXATION TIME, PIXEL MAPPING",

author = "S BARBOSA and LD BLUMHARDT and N ROBERTS and T LOCK and RHT EDWARDS",

year = "1994",

language = "English",

volume = "12",

pages = "33--42",

journal = "Magnetic Resonance Imaging",

issn = "0730-725X",

publisher = "Elsevier Inc.",

number = "1",

}

TY - JOUR

T1 - MAGNETIC-RESONANCE RELAXATION-TIME MAPPING IN MULTIPLE-SCLEROSIS - NORMAL APPEARING WHITE-MATTER AND THE INVISIBLE LESION LOAD

AU - BARBOSA, S

AU - BLUMHARDT, LD

AU - ROBERTS, N

AU - LOCK, T

AU - EDWARDS, RHT

PY - 1994

Y1 - 1994

N2 - Prolonged T-1 and/or T-2 relaxation times (RT) in the normal appearing white matter (NAWM) of patients with multiple sclerosis (MS) have been attributed either to a diffuse abnormality, or to ''small lesions'' undetected by visual inspection of conventional MR images. In a comparison of brain slices from five MS patients and five healthy control subjects, we have confirmed that the average T-1 and T-2 RTs obtained from NAWM in patients with MS are significantly prolonged (p

AB - Prolonged T-1 and/or T-2 relaxation times (RT) in the normal appearing white matter (NAWM) of patients with multiple sclerosis (MS) have been attributed either to a diffuse abnormality, or to ''small lesions'' undetected by visual inspection of conventional MR images. In a comparison of brain slices from five MS patients and five healthy control subjects, we have confirmed that the average T-1 and T-2 RTs obtained from NAWM in patients with MS are significantly prolonged (p

KW - MRI

KW - MULTIPLE SCLEROSIS

KW - NORMAL APPEARING WHITE MATTER

KW - T-1 AND T-2 RELAXATION TIME

KW - PIXEL MAPPING

M3 - Article

VL - 12

SP - 33

EP - 42

JO - Magnetic Resonance Imaging

JF - Magnetic Resonance Imaging

SN - 0730-725X

IS - 1

ER -