Projects per year
Abstract / Description of output
Nature’s molecular machines are a constant source of inspiration to the chemist. Many of these molecular machines function within lipid membranes, allowing them to exploit potential gradients between spatially close, but chemically distinct environments to fuel their work cycle. Indeed, the realisation of such principles in synthetic transmembrane systems remains a tantalising goal. This tutorial review opens by highlighting seminal examples of synthetic molecular machines. We illustrate the importance of surfaces for facilitating the extraction of work from molecular switches and motors. We chart the development of man-made transmembrane systems; from passive to machine-like stimuli-responsive channels, to fully autonomous transmembrane molecular machines. Finally, we highlight higher-order compartmentalised systems that exhibit emergent properties. We suggest that such higher-order architectures could serve as platforms for sophisticated devices that co-ordinate the activity of numerous transmembrane molecular machines.
Original language | English |
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Journal | Chemical Society Reviews |
Early online date | 2 Mar 2016 |
DOIs | |
Publication status | E-pub ahead of print - 2 Mar 2016 |
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- 2 Finished
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Organic supramolecular chemistry: A Research programme of synthetic molecular motors and machines
Leigh, D.
1/01/10 → 30/12/14
Project: Research