Management of anaphylaxis due to COVID-19 vaccines in the elderly

Jean Bousquet; Ioana Agache; Hubert Blain; Marek Jutel; Maria Teresa Ventura; Margitta Worm; Stefano Del Giacco; Athanasios Benetos; M Beatrice Bilo; Wienczyslawa Czarlewski; Amir Hamzah Abdul Latiff; Mona Al-Ahmad; Elizabeth Angier; Isabella Annesi-Maesano; Marina Atanaskovic-Markovic; Claus Bachert; Annick Barbaud; Anna Bedbrook; Kazi S Bennoor; Elena Camelia Berghea; Carsten Bindslev-Jensen; Sergio Bonini; Sinthia Bosnic-Anticevich; Knut Brockow; Luisa Brussino; Paulo Camargos; G Walter Canonica; Victoria Cardona; Pedro Carreiro-Martins; Ana Carriazo; Thomas Casale; Jean-Christoph Caubet; Lorenzo Cecchi; Antonio Cherubini; George Christoff; Derek K Chu; Alvaro A Cruz; Dejan Dokic; Yehia El-Gamal; Motohiro Ebisawa; Bernadette Eberlein; John Farrell; Montserrat Fernandez-Rivas; Wytske J Fokkens; Joao A Fonseca; Yadong Gao; Gaëtan Gavazzi; Radolslaw Gawlik; Asli Gelincik; Bilun Gemicioğlu; Maia Gotua; Olivier Guérin; Tari Haahtela; Karin Hoffmann-Sommergruber; Hans Jürgen Hoffmann; Maja Hofmann; Martin Hrubisko; Madda lenaIllario; Carla Irani; Zhanat Ispayeva; Juan Carlos Ivancevich; Kaja Julge; Igor Kaidashev; Musa Khaitov; Edward Knol; Helga Kraxner; Piotr Kuna; Violeta Kvedariene; Antti Lauerma; Lan Tt Le; Vincent Le Moing; Michael Levin; Renaud Louis; Olga Lourenco; Vera Mahler; Finbarr C Martin; Andrea Matucci; Branislava Milenkovic; Stéphanie Miot; Emma Montella; Mario Morais-Almeida; Charlotte G Mortz; Joaquim Mullol; Leyla Namazova-Baranova; Hugo Neffen; Kristof Nekam; Marek Niedoszytko; Mikaëla Odemyr; Robyn E O'Hehir; Yoshitaka Okamoto; Markus Ollert; Oscar Palomares; Nikolaos G Papadopoulos; Petr Panzner; Gianni Passalacqua; Vincenzo Patella; Mirko Petrovic; Oliver Pfaar; Nhân Pham-Thi; Davor Plavec; Todor A Popov; Marysia T Recto; Frederico S Regateiro; Jacques Reynes; Regina E Roller-Winsberger; Yves Rolland; Antonino Romano; Carmen Rondon; Menachem Rottem; Philip W Rouadi; Nathalie Salles; Boleslaw Samolinski; Alexandra F Santos; Faradiba Sarquis Serpa; Joaquin Sastre; Jos M G A Schols; Nicola Scichilone; Anna Sediva; Mohamed H Shamji; Aziz Sheikh; Isabel Skypala; Sylwia Smolinska; Milena Sokolowska; Bernardo Sousa-Pinto; Milan Sova; Rafael Stelmach; Gunter Sturm; Charlotte Suppli Ulrik; Ana Maria Todo-Bom; Sanna Toppila-Salmi; Ioanna Tsiligianni; Maria Torres; Eva Untersmayr; Marilyn Urrutia Pereira; Arunas Valiulis; Joana Vitte; Alessandra Vultaggio; Dana Wallace; Jolanta Walusiak-Skorupa; De-Yun Wang; Susan Waserman; Arzu Yorgancioglu; Osman M Yusuf; Mario Zernotti; Mihaela Zidarn; Tomas Chivato; Cezmi A Akdis; Torsten Zuberbier; Ludger Klimek

doi:10.1111/all.14838

Management of anaphylaxis due to COVID-19 vaccines in the elderly

Jean Bousquet, Ioana Agache, Hubert Blain, Marek Jutel, Maria Teresa Ventura, Margitta Worm, Stefano Del Giacco, Athanasios Benetos, M Beatrice Bilo, Wienczyslawa Czarlewski, Amir Hamzah Abdul Latiff, Mona Al-Ahmad, Elizabeth Angier, Isabella Annesi-Maesano, Marina Atanaskovic-Markovic, Claus Bachert, Annick Barbaud, Anna Bedbrook, Kazi S Bennoor, Elena Camelia BergheaCarsten Bindslev-Jensen, Sergio Bonini, Sinthia Bosnic-Anticevich, Knut Brockow, Luisa Brussino, Paulo Camargos, G Walter Canonica, Victoria Cardona, Pedro Carreiro-Martins, Ana Carriazo, Thomas Casale, Jean-Christoph Caubet, Lorenzo Cecchi, Antonio Cherubini, George Christoff, Derek K Chu, Alvaro A Cruz, Dejan Dokic, Yehia El-Gamal, Motohiro Ebisawa, Bernadette Eberlein, John Farrell, Montserrat Fernandez-Rivas, Wytske J Fokkens, Joao A Fonseca, Yadong Gao, Gaëtan Gavazzi, Radolslaw Gawlik, Asli Gelincik, Bilun Gemicioğlu, Maia Gotua, Olivier Guérin, Tari Haahtela, Karin Hoffmann-Sommergruber, Hans Jürgen Hoffmann, Maja Hofmann, Martin Hrubisko, Madda lenaIllario, Carla Irani, Zhanat Ispayeva, Juan Carlos Ivancevich, Kaja Julge, Igor Kaidashev, Musa Khaitov, Edward Knol, Helga Kraxner, Piotr Kuna, Violeta Kvedariene, Antti Lauerma, Lan Tt Le, Vincent Le Moing, Michael Levin, Renaud Louis, Olga Lourenco, Vera Mahler, Finbarr C Martin, Andrea Matucci, Branislava Milenkovic, Stéphanie Miot, Emma Montella, Mario Morais-Almeida, Charlotte G Mortz, Joaquim Mullol, Leyla Namazova-Baranova, Hugo Neffen, Kristof Nekam, Marek Niedoszytko, Mikaëla Odemyr, Robyn E O'Hehir, Yoshitaka Okamoto, Markus Ollert, Oscar Palomares, Nikolaos G Papadopoulos, Petr Panzner, Gianni Passalacqua, Vincenzo Patella, Mirko Petrovic, Oliver Pfaar, Nhân Pham-Thi, Davor Plavec, Todor A Popov, Marysia T Recto, Frederico S Regateiro, Jacques Reynes, Regina E Roller-Winsberger, Yves Rolland, Antonino Romano, Carmen Rondon, Menachem Rottem, Philip W Rouadi, Nathalie Salles, Boleslaw Samolinski, Alexandra F Santos, Faradiba Sarquis Serpa, Joaquin Sastre, Jos M G A Schols, Nicola Scichilone, Anna Sediva, Mohamed H Shamji, Aziz Sheikh, Isabel Skypala, Sylwia Smolinska, Milena Sokolowska, Bernardo Sousa-Pinto, Milan Sova, Rafael Stelmach, Gunter Sturm, Charlotte Suppli Ulrik, Ana Maria Todo-Bom, Sanna Toppila-Salmi, Ioanna Tsiligianni, Maria Torres, Eva Untersmayr, Marilyn Urrutia Pereira, Arunas Valiulis, Joana Vitte, Alessandra Vultaggio, Dana Wallace, Jolanta Walusiak-Skorupa, De-Yun Wang, Susan Waserman, Arzu Yorgancioglu, Osman M Yusuf, Mario Zernotti, Mihaela Zidarn, Tomas Chivato, Cezmi A Akdis, Torsten Zuberbier, Ludger Klimek

Research output: Contribution to journal › Article › peer-review

Abstract

Older adults, especially men and/or those with diabetes, hypertension and/or obesity, are prone to severe COVID-19. In some countries, older adults, particularly those residing in nursing homes, have been prioritised to receive COVID-19 vaccines due to high risk of death. In very rare instances,the COVID-19 vaccines can induce anaphylaxis, and the management of anaphylaxis in older people should be considered carefully. An ARIA-EAACI-EuGMS (Allergic Rhinitis and its Impact on Asthma, European Academy of Allergy and Clinical Immunology, and European Geriatric Medicine Society)Working Group has proposed some recommendations for older adults receiving the COVID-19 vaccines. Anaphylaxis to COVID-19 vaccines is extremely rare (from 1 per 100,000 to 5 per million injections). Symptoms are similar in younger and older adults but they tend to be more severe in the older patients. Adrenaline is the mainstay treatment and should be readily available. A flowchart is proposed to manage anaphylaxis in the older patients.

Original language	English
Journal	Allergy
Early online date	2 Apr 2021
DOIs	https://doi.org/10.1111/all.14838
Publication status	E-pub ahead of print - 2 Apr 2021

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10.1111/all.14838

Management of anaphylaxis due to COVID‐19 vaccines in the elderlyAccepted author manuscript, 1.08 MB

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Bousquet, J., Agache, I., Blain, H., Jutel, M., Ventura, M. T., Worm, M., Del Giacco, S., Benetos, A., Bilo, M. B., Czarlewski, W., Abdul Latiff, A. H., Al-Ahmad, M., Angier, E., Annesi-Maesano, I., Atanaskovic-Markovic, M., Bachert, C., Barbaud, A., Bedbrook, A., Bennoor, K. S., ... Klimek, L. (2021). Management of anaphylaxis due to COVID-19 vaccines in the elderly. Allergy. Advance online publication. https://doi.org/10.1111/all.14838

@article{47d1987bd0fe4c5db1882875eb44c9dc,

title = "Management of anaphylaxis due to COVID-19 vaccines in the elderly",

abstract = "Older adults, especially men and/or those with diabetes, hypertension and/or obesity, are prone to severe COVID-19. In some countries, older adults, particularly those residing in nursing homes, have been prioritised to receive COVID-19 vaccines due to high risk of death. In very rare instances,the COVID-19 vaccines can induce anaphylaxis, and the management of anaphylaxis in older people should be considered carefully. An ARIA-EAACI-EuGMS (Allergic Rhinitis and its Impact on Asthma, European Academy of Allergy and Clinical Immunology, and European Geriatric Medicine Society)Working Group has proposed some recommendations for older adults receiving the COVID-19 vaccines. Anaphylaxis to COVID-19 vaccines is extremely rare (from 1 per 100,000 to 5 per million injections). Symptoms are similar in younger and older adults but they tend to be more severe in the older patients. Adrenaline is the mainstay treatment and should be readily available. A flowchart is proposed to manage anaphylaxis in the older patients.",

author = "Jean Bousquet and Ioana Agache and Hubert Blain and Marek Jutel and Ventura, {Maria Teresa} and Margitta Worm and {Del Giacco}, Stefano and Athanasios Benetos and Bilo, {M Beatrice} and Wienczyslawa Czarlewski and {Abdul Latiff}, {Amir Hamzah} and Mona Al-Ahmad and Elizabeth Angier and Isabella Annesi-Maesano and Marina Atanaskovic-Markovic and Claus Bachert and Annick Barbaud and Anna Bedbrook and Bennoor, {Kazi S} and Berghea, {Elena Camelia} and Carsten Bindslev-Jensen and Sergio Bonini and Sinthia Bosnic-Anticevich and Knut Brockow and Luisa Brussino and Paulo Camargos and Canonica, {G Walter} and Victoria Cardona and Pedro Carreiro-Martins and Ana Carriazo and Thomas Casale and Jean-Christoph Caubet and Lorenzo Cecchi and Antonio Cherubini and George Christoff and Chu, {Derek K} and Cruz, {Alvaro A} and Dejan Dokic and Yehia El-Gamal and Motohiro Ebisawa and Bernadette Eberlein and John Farrell and Montserrat Fernandez-Rivas and Fokkens, {Wytske J} and Fonseca, {Joao A} and Yadong Gao and Ga{\"e}tan Gavazzi and Radolslaw Gawlik and Asli Gelincik and Bilun Gemicioğlu and Maia Gotua and Olivier Gu{\'e}rin and Tari Haahtela and Karin Hoffmann-Sommergruber and Hoffmann, {Hans J{\"u}rgen} and Maja Hofmann and Martin Hrubisko and Madda lenaIllario and Carla Irani and Zhanat Ispayeva and Ivancevich, {Juan Carlos} and Kaja Julge and Igor Kaidashev and Musa Khaitov and Edward Knol and Helga Kraxner and Piotr Kuna and Violeta Kvedariene and Antti Lauerma and Le, {Lan Tt} and {Le Moing}, Vincent and Michael Levin and Renaud Louis and Olga Lourenco and Vera Mahler and Martin, {Finbarr C} and Andrea Matucci and Branislava Milenkovic and St{\'e}phanie Miot and Emma Montella and Mario Morais-Almeida and Mortz, {Charlotte G} and Joaquim Mullol and Leyla Namazova-Baranova and Hugo Neffen and Kristof Nekam and Marek Niedoszytko and Mika{\"e}la Odemyr and O'Hehir, {Robyn E} and Yoshitaka Okamoto and Markus Ollert and Oscar Palomares and Papadopoulos, {Nikolaos G} and Petr Panzner and Gianni Passalacqua and Vincenzo Patella and Mirko Petrovic and Oliver Pfaar and Nh{\^a}n Pham-Thi and Davor Plavec and Popov, {Todor A} and Recto, {Marysia T} and Regateiro, {Frederico S} and Jacques Reynes and Roller-Winsberger, {Regina E} and Yves Rolland and Antonino Romano and Carmen Rondon and Menachem Rottem and Rouadi, {Philip W} and Nathalie Salles and Boleslaw Samolinski and Santos, {Alexandra F} and Serpa, {Faradiba Sarquis} and Joaquin Sastre and Schols, {Jos M G A} and Nicola Scichilone and Anna Sediva and Shamji, {Mohamed H} and Aziz Sheikh and Isabel Skypala and Sylwia Smolinska and Milena Sokolowska and Bernardo Sousa-Pinto and Milan Sova and Rafael Stelmach and Gunter Sturm and {Suppli Ulrik}, Charlotte and Todo-Bom, {Ana Maria} and Sanna Toppila-Salmi and Ioanna Tsiligianni and Maria Torres and Eva Untersmayr and {Urrutia Pereira}, Marilyn and Arunas Valiulis and Joana Vitte and Alessandra Vultaggio and Dana Wallace and Jolanta Walusiak-Skorupa and De-Yun Wang and Susan Waserman and Arzu Yorgancioglu and Yusuf, {Osman M} and Mario Zernotti and Mihaela Zidarn and Tomas Chivato and Akdis, {Cezmi A} and Torsten Zuberbier and Ludger Klimek",

year = "2021",

month = apr,

day = "2",

doi = "10.1111/all.14838",

language = "English",

journal = "Allergy",

issn = "0105-4538",

publisher = "Wiley-Blackwell",

}

Bousquet, J, Agache, I, Blain, H, Jutel, M, Ventura, MT, Worm, M, Del Giacco, S, Benetos, A, Bilo, MB, Czarlewski, W, Abdul Latiff, AH, Al-Ahmad, M, Angier, E, Annesi-Maesano, I, Atanaskovic-Markovic, M, Bachert, C, Barbaud, A, Bedbrook, A, Bennoor, KS, Berghea, EC, Bindslev-Jensen, C, Bonini, S, Bosnic-Anticevich, S, Brockow, K, Brussino, L, Camargos, P, Canonica, GW, Cardona, V, Carreiro-Martins, P, Carriazo, A, Casale, T, Caubet, J-C, Cecchi, L, Cherubini, A, Christoff, G, Chu, DK, Cruz, AA, Dokic, D, El-Gamal, Y, Ebisawa, M, Eberlein, B, Farrell, J, Fernandez-Rivas, M, Fokkens, WJ, Fonseca, JA, Gao, Y, Gavazzi, G, Gawlik, R, Gelincik, A, Gemicioğlu, B, Gotua, M, Guérin, O, Haahtela, T, Hoffmann-Sommergruber, K, Hoffmann, HJ, Hofmann, M, Hrubisko, M, lenaIllario, M, Irani, C, Ispayeva, Z, Ivancevich, JC, Julge, K, Kaidashev, I, Khaitov, M, Knol, E, Kraxner, H, Kuna, P, Kvedariene, V, Lauerma, A, Le, LT, Le Moing, V, Levin, M, Louis, R, Lourenco, O, Mahler, V, Martin, FC, Matucci, A, Milenkovic, B, Miot, S, Montella, E, Morais-Almeida, M, Mortz, CG, Mullol, J, Namazova-Baranova, L, Neffen, H, Nekam, K, Niedoszytko, M, Odemyr, M, O'Hehir, RE, Okamoto, Y, Ollert, M, Palomares, O, Papadopoulos, NG, Panzner, P, Passalacqua, G, Patella, V, Petrovic, M, Pfaar, O, Pham-Thi, N, Plavec, D, Popov, TA, Recto, MT, Regateiro, FS, Reynes, J, Roller-Winsberger, RE, Rolland, Y, Romano, A, Rondon, C, Rottem, M, Rouadi, PW, Salles, N, Samolinski, B, Santos, AF, Serpa, FS, Sastre, J, Schols, JMGA, Scichilone, N, Sediva, A, Shamji, MH, Sheikh, A, Skypala, I, Smolinska, S, Sokolowska, M, Sousa-Pinto, B, Sova, M, Stelmach, R, Sturm, G, Suppli Ulrik, C, Todo-Bom, AM, Toppila-Salmi, S, Tsiligianni, I, Torres, M, Untersmayr, E, Urrutia Pereira, M, Valiulis, A, Vitte, J, Vultaggio, A, Wallace, D, Walusiak-Skorupa, J, Wang, D-Y, Waserman, S, Yorgancioglu, A, Yusuf, OM, Zernotti, M, Zidarn, M, Chivato, T, Akdis, CA, Zuberbier, T & Klimek, L 2021, 'Management of anaphylaxis due to COVID-19 vaccines in the elderly', Allergy. https://doi.org/10.1111/all.14838

TY - JOUR

T1 - Management of anaphylaxis due to COVID-19 vaccines in the elderly

AU - Bousquet, Jean

AU - Agache, Ioana

AU - Blain, Hubert

AU - Jutel, Marek

AU - Ventura, Maria Teresa

AU - Worm, Margitta

AU - Del Giacco, Stefano

AU - Benetos, Athanasios

AU - Bilo, M Beatrice

AU - Czarlewski, Wienczyslawa

AU - Abdul Latiff, Amir Hamzah

AU - Al-Ahmad, Mona

AU - Angier, Elizabeth

AU - Annesi-Maesano, Isabella

AU - Atanaskovic-Markovic, Marina

AU - Bachert, Claus

AU - Barbaud, Annick

AU - Bedbrook, Anna

AU - Bennoor, Kazi S

AU - Berghea, Elena Camelia

AU - Bindslev-Jensen, Carsten

AU - Bonini, Sergio

AU - Bosnic-Anticevich, Sinthia

AU - Brockow, Knut

AU - Brussino, Luisa

AU - Camargos, Paulo

AU - Canonica, G Walter

AU - Cardona, Victoria

AU - Carreiro-Martins, Pedro

AU - Carriazo, Ana

AU - Casale, Thomas

AU - Caubet, Jean-Christoph

AU - Cecchi, Lorenzo

AU - Cherubini, Antonio

AU - Christoff, George

AU - Chu, Derek K

AU - Cruz, Alvaro A

AU - Dokic, Dejan

AU - El-Gamal, Yehia

AU - Ebisawa, Motohiro

AU - Eberlein, Bernadette

AU - Farrell, John

AU - Fernandez-Rivas, Montserrat

AU - Fokkens, Wytske J

AU - Fonseca, Joao A

AU - Gao, Yadong

AU - Gavazzi, Gaëtan

AU - Gawlik, Radolslaw

AU - Gelincik, Asli

AU - Gemicioğlu, Bilun

AU - Gotua, Maia

AU - Guérin, Olivier

AU - Haahtela, Tari

AU - Hoffmann-Sommergruber, Karin

AU - Hoffmann, Hans Jürgen

AU - Hofmann, Maja

AU - Hrubisko, Martin

AU - lenaIllario, Madda

AU - Irani, Carla

AU - Ispayeva, Zhanat

AU - Ivancevich, Juan Carlos

AU - Julge, Kaja

AU - Kaidashev, Igor

AU - Khaitov, Musa

AU - Knol, Edward

AU - Kraxner, Helga

AU - Kuna, Piotr

AU - Kvedariene, Violeta

AU - Lauerma, Antti

AU - Le, Lan Tt

AU - Le Moing, Vincent

AU - Levin, Michael

AU - Louis, Renaud

AU - Lourenco, Olga

AU - Mahler, Vera

AU - Martin, Finbarr C

AU - Matucci, Andrea

AU - Milenkovic, Branislava

AU - Miot, Stéphanie

AU - Montella, Emma

AU - Morais-Almeida, Mario

AU - Mortz, Charlotte G

AU - Mullol, Joaquim

AU - Namazova-Baranova, Leyla

AU - Neffen, Hugo

AU - Nekam, Kristof

AU - Niedoszytko, Marek

AU - Odemyr, Mikaëla

AU - O'Hehir, Robyn E

AU - Okamoto, Yoshitaka

AU - Ollert, Markus

AU - Palomares, Oscar

AU - Papadopoulos, Nikolaos G

AU - Panzner, Petr

AU - Passalacqua, Gianni

AU - Patella, Vincenzo

AU - Petrovic, Mirko

AU - Pfaar, Oliver

AU - Pham-Thi, Nhân

AU - Plavec, Davor

AU - Popov, Todor A

AU - Recto, Marysia T

AU - Regateiro, Frederico S

AU - Reynes, Jacques

AU - Roller-Winsberger, Regina E

AU - Rolland, Yves

AU - Romano, Antonino

AU - Rondon, Carmen

AU - Rottem, Menachem

AU - Rouadi, Philip W

AU - Salles, Nathalie

AU - Samolinski, Boleslaw

AU - Santos, Alexandra F

AU - Serpa, Faradiba Sarquis

AU - Sastre, Joaquin

AU - Schols, Jos M G A

AU - Scichilone, Nicola

AU - Sediva, Anna

AU - Shamji, Mohamed H

AU - Sheikh, Aziz

AU - Skypala, Isabel

AU - Smolinska, Sylwia

AU - Sokolowska, Milena

AU - Sousa-Pinto, Bernardo

AU - Sova, Milan

AU - Stelmach, Rafael

AU - Sturm, Gunter

AU - Suppli Ulrik, Charlotte

AU - Todo-Bom, Ana Maria

AU - Toppila-Salmi, Sanna

AU - Tsiligianni, Ioanna

AU - Torres, Maria

AU - Untersmayr, Eva

AU - Urrutia Pereira, Marilyn

AU - Valiulis, Arunas

AU - Vitte, Joana

AU - Vultaggio, Alessandra

AU - Wallace, Dana

AU - Walusiak-Skorupa, Jolanta

AU - Wang, De-Yun

AU - Waserman, Susan

AU - Yorgancioglu, Arzu

AU - Yusuf, Osman M

AU - Zernotti, Mario

AU - Zidarn, Mihaela

AU - Chivato, Tomas

AU - Akdis, Cezmi A

AU - Zuberbier, Torsten

AU - Klimek, Ludger

PY - 2021/4/2

Y1 - 2021/4/2

N2 - Older adults, especially men and/or those with diabetes, hypertension and/or obesity, are prone to severe COVID-19. In some countries, older adults, particularly those residing in nursing homes, have been prioritised to receive COVID-19 vaccines due to high risk of death. In very rare instances,the COVID-19 vaccines can induce anaphylaxis, and the management of anaphylaxis in older people should be considered carefully. An ARIA-EAACI-EuGMS (Allergic Rhinitis and its Impact on Asthma, European Academy of Allergy and Clinical Immunology, and European Geriatric Medicine Society)Working Group has proposed some recommendations for older adults receiving the COVID-19 vaccines. Anaphylaxis to COVID-19 vaccines is extremely rare (from 1 per 100,000 to 5 per million injections). Symptoms are similar in younger and older adults but they tend to be more severe in the older patients. Adrenaline is the mainstay treatment and should be readily available. A flowchart is proposed to manage anaphylaxis in the older patients.

AB - Older adults, especially men and/or those with diabetes, hypertension and/or obesity, are prone to severe COVID-19. In some countries, older adults, particularly those residing in nursing homes, have been prioritised to receive COVID-19 vaccines due to high risk of death. In very rare instances,the COVID-19 vaccines can induce anaphylaxis, and the management of anaphylaxis in older people should be considered carefully. An ARIA-EAACI-EuGMS (Allergic Rhinitis and its Impact on Asthma, European Academy of Allergy and Clinical Immunology, and European Geriatric Medicine Society)Working Group has proposed some recommendations for older adults receiving the COVID-19 vaccines. Anaphylaxis to COVID-19 vaccines is extremely rare (from 1 per 100,000 to 5 per million injections). Symptoms are similar in younger and older adults but they tend to be more severe in the older patients. Adrenaline is the mainstay treatment and should be readily available. A flowchart is proposed to manage anaphylaxis in the older patients.

U2 - 10.1111/all.14838

DO - 10.1111/all.14838

M3 - Article

C2 - 33811358

SN - 0105-4538

JO - Allergy

JF - Allergy

ER -

Management of anaphylaxis due to COVID-19 vaccines in the elderly

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