Mapping the genomic basis of developmental and metabolic responses to nitrogen

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Nitrogen (N) is an essential macronutrient that regulates developmental and physiological responses in plants. Although phenotypic and metabolic responses to N in different forms and concentrations have been extensively reported (reviewed in Fredes et al., 2019), these studies have largely focused on the model plant Arabidopsis thaliana accession Columbia (Col-0), and how this information translates to natural variation in N responses is less understood. In this issue of The Plant Cell, Ella Katz and colleagues (Katz et al., 2022) use over a thousand accessions to map various new loci underpinning responses to different N regimens in Arabidopsis. Interestingly, the authors present evidence that combinations of many small effect loci, rather than a few large effect loci, modulate N responses, suggesting that synthetic manipulation of sets of genes is a promising strategy to improve N use efficiency in plants.
Original languageEnglish
Article numberkoac291
Pages (from-to)4663-4664
Number of pages2
JournalThe Plant cell
Issue number12
Early online date27 Sep 2022
Publication statusPublished - 1 Dec 2022


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