Markers of adenocarcinoma characteristic of the site of origin: development of a diagnostic algorithm

Jayne L Dennis, Torgeir R Hvidsten, Ernst C Wit, Jan Komorowski, Alexandra K Bell, Ian Downie, Jacqueline Mooney, Caroline Verbeke, Christopher Bellamy, W Nicol Keith, Karin A Oien

Research output: Contribution to journalArticlepeer-review

Abstract

Patients with metastatic adenocarcinoma of unknown origin are a common clinical problem. Knowledge of the primary site is important for their management, but histologically, such tumors appear similar. Better diagnostic markers are needed to enable the assignment of metastases to likely sites of origin on pathologic samples.
Original languageEnglish
Pages (from-to)3766-72
Number of pages7
JournalClinical Cancer Research
Volume11
Issue number10
DOIs
Publication statusPublished - 15 May 2005

Keywords

  • Adenocarcinoma
  • Biopsy
  • Diagnosis, Differential
  • Humans
  • Immunohistochemistry
  • In Situ Hybridization
  • Neoplasms, Unknown Primary
  • Predictive Value of Tests
  • Sensitivity and Specificity
  • Tumor Markers, Biological

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