Mathematical model of the Arabidopsis circadian clock: Pokhilko 2012 model

Alexandra Pokhilko; Andrew Millar

Mathematical model of the Arabidopsis circadian clock: Pokhilko 2012 model

Alexandra Pokhilko, Andrew Millar

School of Biological Sciences

Research output: Other contribution

Abstract

The model is termed P2012 and derives from the article: Modelling the widespread effects of TOC1 signalling on the plant circadian clock and its outputs. Alexandra Pokhilko, Paloma Mas & Andrew J Millar BMC Syst. Biol. 2013; 7: 23, submitted 10 Oct 2012 and published 19 March 2013.

The model describes the circuit depicted in Fig. 1 of the paper. It updates the P2011 model from Pokhilko et al. Mol. Syst. Biol. 2012 model, PLM_64, by including:

TOC1 as a repressor of multiple clock genes, rather than only of LHY/CCA1.
ABAR transcription modified by TOC1, affecting stomatal aperture.
TOC1 transcription modified by ABA.

SBML curation notes on PlaSMo (please see Comments for each version):

PLM_70 version 1 is the version published as Supplementary Information and submitted to the Biomodels database.

Copasi and MATLAB versions are attached to version 1.

This model has formed the basis for further work by external groups, as described in the following links:
http://dx.doi.org/10.3389/fpls.2016.00074
http://dx.doi.org/10.1038/nature14449

Original language	English
Type	P2012 model
Media of output	Database records, various formats
Publication status	Published - 2013

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1 Finished

TiMet: Linking the clock to metabolism
Millar, A.
EU government bodies
1/03/10 → 28/02/15
Project: Research

1 Article

Modelling the widespread effects of TOC1 signalling on the plant circadian clock and its outputs
Pokhilko, A., Mas, P. & Millar, A. J., 2013, In: BMC Systems Biology. 7, 1, 12 p., 23.
Research output: Contribution to journal › Article › peer-review

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title = "Mathematical model of the Arabidopsis circadian clock: Pokhilko 2012 model",

abstract = "The model is termed P2012 and derives from the article: Modelling the widespread effects of TOC1 signalling on the plant circadian clock and its outputs. Alexandra Pokhilko, Paloma Mas & Andrew J Millar BMC Syst. Biol. 2013; 7: 23, submitted 10 Oct 2012 and published 19 March 2013. The model describes the circuit depicted in Fig. 1 of the paper. It updates the P2011 model from Pokhilko et al. Mol. Syst. Biol. 2012 model, PLM_64, by including: TOC1 as a repressor of multiple clock genes, rather than only of LHY/CCA1. ABAR transcription modified by TOC1, affecting stomatal aperture. TOC1 transcription modified by ABA.SBML curation notes on PlaSMo (please see Comments for each version):PLM_70 version 1 is the version published as Supplementary Information and submitted to the Biomodels database.Copasi and MATLAB versions are attached to version 1.This model has formed the basis for further work by external groups, as described in the following links:http://dx.doi.org/10.3389/fpls.2016.00074http://dx.doi.org/10.1038/nature14449",

author = "Alexandra Pokhilko and Andrew Millar",

year = "2013",

language = "English",

type = "Other",

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TY - GEN

T1 - Mathematical model of the Arabidopsis circadian clock: Pokhilko 2012 model

AU - Pokhilko, Alexandra

AU - Millar, Andrew

PY - 2013

Y1 - 2013

N2 - The model is termed P2012 and derives from the article: Modelling the widespread effects of TOC1 signalling on the plant circadian clock and its outputs. Alexandra Pokhilko, Paloma Mas & Andrew J Millar BMC Syst. Biol. 2013; 7: 23, submitted 10 Oct 2012 and published 19 March 2013. The model describes the circuit depicted in Fig. 1 of the paper. It updates the P2011 model from Pokhilko et al. Mol. Syst. Biol. 2012 model, PLM_64, by including: TOC1 as a repressor of multiple clock genes, rather than only of LHY/CCA1. ABAR transcription modified by TOC1, affecting stomatal aperture. TOC1 transcription modified by ABA.SBML curation notes on PlaSMo (please see Comments for each version):PLM_70 version 1 is the version published as Supplementary Information and submitted to the Biomodels database.Copasi and MATLAB versions are attached to version 1.This model has formed the basis for further work by external groups, as described in the following links:http://dx.doi.org/10.3389/fpls.2016.00074http://dx.doi.org/10.1038/nature14449

AB - The model is termed P2012 and derives from the article: Modelling the widespread effects of TOC1 signalling on the plant circadian clock and its outputs. Alexandra Pokhilko, Paloma Mas & Andrew J Millar BMC Syst. Biol. 2013; 7: 23, submitted 10 Oct 2012 and published 19 March 2013. The model describes the circuit depicted in Fig. 1 of the paper. It updates the P2011 model from Pokhilko et al. Mol. Syst. Biol. 2012 model, PLM_64, by including: TOC1 as a repressor of multiple clock genes, rather than only of LHY/CCA1. ABAR transcription modified by TOC1, affecting stomatal aperture. TOC1 transcription modified by ABA.SBML curation notes on PlaSMo (please see Comments for each version):PLM_70 version 1 is the version published as Supplementary Information and submitted to the Biomodels database.Copasi and MATLAB versions are attached to version 1.This model has formed the basis for further work by external groups, as described in the following links:http://dx.doi.org/10.3389/fpls.2016.00074http://dx.doi.org/10.1038/nature14449

M3 - Other contribution

ER -

Mathematical model of the Arabidopsis circadian clock: Pokhilko 2012 model

Abstract

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Projects

TiMet: Linking the clock to metabolism

Research output

Modelling the widespread effects of TOC1 signalling on the plant circadian clock and its outputs

Cite this