TY - JOUR
T1 - MaxSynBio
T2 - Avenues Towards Creating Cells from the Bottom Up
AU - Schwille, Petra
AU - Spatz, Joachim
AU - Landfester, Katharina
AU - Bodenschatz, Eberhard
AU - Herminghaus, Stephan
AU - Sourjik, Victor
AU - Erb, Tobias J.
AU - Bastiaens, Philippe
AU - Lipowsky, Reinhard
AU - Hyman, Anthony
AU - Dabrock, Peter
AU - Baret, Jean Christophe
AU - Vidakovic-Koch, Tanja
AU - Bieling, Peter
AU - Dimova, Rumiana
AU - Mutschler, Hannes
AU - Robinson, Tom
AU - Tang, T. Y.Dora
AU - Wegner, Seraphine
AU - Sundmacher, Kai
PY - 2018/10/4
Y1 - 2018/10/4
N2 - A large German research consortium mainly within the Max Planck Society (“MaxSynBio”) was formed to investigate living systems from a fundamental perspective. The research program of MaxSynBio relies solely on the bottom-up approach to synthetic biology. MaxSynBio focuses on the detailed analysis and understanding of essential processes of life through modular reconstitution in minimal synthetic systems. The ultimate goal is to construct a basic living unit entirely from non-living components. The fundamental insights gained from the activities in MaxSynBio could eventually be utilized for establishing a new generation of biotechnological processes, which would be based on synthetic cell constructs that replace the natural cells currently used in conventional biotechnology.
AB - A large German research consortium mainly within the Max Planck Society (“MaxSynBio”) was formed to investigate living systems from a fundamental perspective. The research program of MaxSynBio relies solely on the bottom-up approach to synthetic biology. MaxSynBio focuses on the detailed analysis and understanding of essential processes of life through modular reconstitution in minimal synthetic systems. The ultimate goal is to construct a basic living unit entirely from non-living components. The fundamental insights gained from the activities in MaxSynBio could eventually be utilized for establishing a new generation of biotechnological processes, which would be based on synthetic cell constructs that replace the natural cells currently used in conventional biotechnology.
KW - biotechnology
KW - bottom-up design
KW - microfluidics
KW - protocells
KW - synthetic biology
UR - http://www.scopus.com/inward/record.url?scp=85051864548&partnerID=8YFLogxK
U2 - 10.1002/anie.201802288
DO - 10.1002/anie.201802288
M3 - Review article
C2 - 29749673
AN - SCOPUS:85051864548
SN - 1433-7851
VL - 57
SP - 13382
EP - 13392
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
IS - 41
ER -