Measurement of renal function in patients with chronic kidney disease

Euan A. Sandilands; Neeraj Dhaun; James W. Dear; David J. Webb

doi:10.1111/bcp.12198

Measurement of renal function in patients with chronic kidney disease

Euan A. Sandilands^*, Neeraj Dhaun, James W. Dear, David J. Webb

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Chronic kidney disease affects millions of people worldwide and is associated with an increased morbidity and mortality as a result of kidney failure and cardiovascular disease. Accurate assessment of kidney function is important in the clinical setting as a screening tool and for monitoring disease progression and guiding prognosis. In clinical research, the development of new methods to measure kidney function accurately is important in the search for new therapeutic targets and the discovery of novel biomarkers to aid early identification of kidney injury. This review considers different methods for measuring kidney function and their contribution to the improvement of detection, monitoring and treatment of chronic kidney disease.

Original language	English
Pages (from-to)	504-515
Number of pages	12
Journal	British Journal of Clinical Pharmacology
Volume	76
Issue number	4
DOIs	https://doi.org/10.1111/bcp.12198
Publication status	Published - Oct 2013

Keywords

chronic kidney disease
glomerular filtration rate
renal dysfunction
GLOMERULAR-FILTRATION-RATE
SERUM CYSTATIN-C
GELATINASE-ASSOCIATED LIPOCALIN
PROTEIN-CREATININE RATIO
INJURY MOLECULE-1 KIM-1
ACID-BINDING PROTEIN
TRANSPLANT RECIPIENTS
PLASMA-CLEARANCE
HYPERTENSIVE PATIENTS
I-125 IOTHALAMATE

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10.1111/bcp.12198

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title = "Measurement of renal function in patients with chronic kidney disease",

abstract = "Chronic kidney disease affects millions of people worldwide and is associated with an increased morbidity and mortality as a result of kidney failure and cardiovascular disease. Accurate assessment of kidney function is important in the clinical setting as a screening tool and for monitoring disease progression and guiding prognosis. In clinical research, the development of new methods to measure kidney function accurately is important in the search for new therapeutic targets and the discovery of novel biomarkers to aid early identification of kidney injury. This review considers different methods for measuring kidney function and their contribution to the improvement of detection, monitoring and treatment of chronic kidney disease.",

keywords = "chronic kidney disease, glomerular filtration rate, renal dysfunction, GLOMERULAR-FILTRATION-RATE, SERUM CYSTATIN-C, GELATINASE-ASSOCIATED LIPOCALIN, PROTEIN-CREATININE RATIO, INJURY MOLECULE-1 KIM-1, ACID-BINDING PROTEIN, TRANSPLANT RECIPIENTS, PLASMA-CLEARANCE, HYPERTENSIVE PATIENTS, I-125 IOTHALAMATE",

author = "Sandilands, {Euan A.} and Neeraj Dhaun and Dear, {James W.} and Webb, {David J.}",

year = "2013",

month = oct,

doi = "10.1111/bcp.12198",

language = "English",

volume = "76",

pages = "504--515",

journal = "British Journal of Clinical Pharmacology",

issn = "0306-5251",

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TY - JOUR

T1 - Measurement of renal function in patients with chronic kidney disease

AU - Sandilands, Euan A.

AU - Dhaun, Neeraj

AU - Dear, James W.

AU - Webb, David J.

PY - 2013/10

Y1 - 2013/10

N2 - Chronic kidney disease affects millions of people worldwide and is associated with an increased morbidity and mortality as a result of kidney failure and cardiovascular disease. Accurate assessment of kidney function is important in the clinical setting as a screening tool and for monitoring disease progression and guiding prognosis. In clinical research, the development of new methods to measure kidney function accurately is important in the search for new therapeutic targets and the discovery of novel biomarkers to aid early identification of kidney injury. This review considers different methods for measuring kidney function and their contribution to the improvement of detection, monitoring and treatment of chronic kidney disease.

AB - Chronic kidney disease affects millions of people worldwide and is associated with an increased morbidity and mortality as a result of kidney failure and cardiovascular disease. Accurate assessment of kidney function is important in the clinical setting as a screening tool and for monitoring disease progression and guiding prognosis. In clinical research, the development of new methods to measure kidney function accurately is important in the search for new therapeutic targets and the discovery of novel biomarkers to aid early identification of kidney injury. This review considers different methods for measuring kidney function and their contribution to the improvement of detection, monitoring and treatment of chronic kidney disease.

KW - chronic kidney disease

KW - glomerular filtration rate

KW - renal dysfunction

KW - GLOMERULAR-FILTRATION-RATE

KW - SERUM CYSTATIN-C

KW - GELATINASE-ASSOCIATED LIPOCALIN

KW - PROTEIN-CREATININE RATIO

KW - INJURY MOLECULE-1 KIM-1

KW - ACID-BINDING PROTEIN

KW - TRANSPLANT RECIPIENTS

KW - PLASMA-CLEARANCE

KW - HYPERTENSIVE PATIENTS

KW - I-125 IOTHALAMATE

U2 - 10.1111/bcp.12198

DO - 10.1111/bcp.12198

M3 - Article

VL - 76

SP - 504

EP - 515

JO - British Journal of Clinical Pharmacology

JF - British Journal of Clinical Pharmacology

SN - 0306-5251

IS - 4

ER -

Measurement of renal function in patients with chronic kidney disease

Abstract

Keywords

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