Abstract
Chronic kidney disease affects millions of people worldwide and is associated with an increased morbidity and mortality as a result of kidney failure and cardiovascular disease. Accurate assessment of kidney function is important in the clinical setting as a screening tool and for monitoring disease progression and guiding prognosis. In clinical research, the development of new methods to measure kidney function accurately is important in the search for new therapeutic targets and the discovery of novel biomarkers to aid early identification of kidney injury. This review considers different methods for measuring kidney function and their contribution to the improvement of detection, monitoring and treatment of chronic kidney disease.
Original language | English |
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Pages (from-to) | 504-515 |
Number of pages | 12 |
Journal | British Journal of Clinical Pharmacology |
Volume | 76 |
Issue number | 4 |
DOIs | |
Publication status | Published - Oct 2013 |
Keywords
- chronic kidney disease
- glomerular filtration rate
- renal dysfunction
- GLOMERULAR-FILTRATION-RATE
- SERUM CYSTATIN-C
- GELATINASE-ASSOCIATED LIPOCALIN
- PROTEIN-CREATININE RATIO
- INJURY MOLECULE-1 KIM-1
- ACID-BINDING PROTEIN
- TRANSPLANT RECIPIENTS
- PLASMA-CLEARANCE
- HYPERTENSIVE PATIENTS
- I-125 IOTHALAMATE