Measurement of renal function in patients with chronic kidney disease

Euan A. Sandilands*, Neeraj Dhaun, James W. Dear, David J. Webb

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Chronic kidney disease affects millions of people worldwide and is associated with an increased morbidity and mortality as a result of kidney failure and cardiovascular disease. Accurate assessment of kidney function is important in the clinical setting as a screening tool and for monitoring disease progression and guiding prognosis. In clinical research, the development of new methods to measure kidney function accurately is important in the search for new therapeutic targets and the discovery of novel biomarkers to aid early identification of kidney injury. This review considers different methods for measuring kidney function and their contribution to the improvement of detection, monitoring and treatment of chronic kidney disease.

Original languageEnglish
Pages (from-to)504-515
Number of pages12
JournalBritish Journal of Clinical Pharmacology
Volume76
Issue number4
DOIs
Publication statusPublished - Oct 2013

Keywords

  • chronic kidney disease
  • glomerular filtration rate
  • renal dysfunction
  • GLOMERULAR-FILTRATION-RATE
  • SERUM CYSTATIN-C
  • GELATINASE-ASSOCIATED LIPOCALIN
  • PROTEIN-CREATININE RATIO
  • INJURY MOLECULE-1 KIM-1
  • ACID-BINDING PROTEIN
  • TRANSPLANT RECIPIENTS
  • PLASMA-CLEARANCE
  • HYPERTENSIVE PATIENTS
  • I-125 IOTHALAMATE

Cite this