Medroxyprogesterone acetate inhibits the cardioprotective effect of estrogen in experimental ischemia-reperfusion injury

Helen L Jeanes; Payong Wanikiat; Isam Sharif; Gillian A Gray

doi:10.1097/01.gme.0000196593.44335.eb

Medroxyprogesterone acetate inhibits the cardioprotective effect of estrogen in experimental ischemia-reperfusion injury

Helen L Jeanes, Payong Wanikiat, Isam Sharif, Gillian A Gray

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

Results from recent clinical trials of estrogen and progestogen therapy (EPT) suggest that some progestogens may interfere with the cardiovascular benefits of estrogen (E). The aim of this study was to investigate whether medroxyprogesterone acetate (MPA) modifies the protective effect of E in experimental ischemia-reperfusion (IR) injury in vivo and in vitro in the rat.

Original language	English
Pages (from-to)	80-6
Number of pages	7
Journal	Menopause
Volume	13
Issue number	1
DOIs	https://doi.org/10.1097/01.gme.0000196593.44335.eb
Publication status	Published - 2006

Access to Document

10.1097/01.gme.0000196593.44335.eb

Cite this

@article{7a149c13949942fcbdffc08e6f557da4,

title = "Medroxyprogesterone acetate inhibits the cardioprotective effect of estrogen in experimental ischemia-reperfusion injury",

abstract = "Results from recent clinical trials of estrogen and progestogen therapy (EPT) suggest that some progestogens may interfere with the cardiovascular benefits of estrogen (E). The aim of this study was to investigate whether medroxyprogesterone acetate (MPA) modifies the protective effect of E in experimental ischemia-reperfusion (IR) injury in vivo and in vitro in the rat.",

author = "Jeanes, {Helen L} and Payong Wanikiat and Isam Sharif and Gray, {Gillian A}",

year = "2006",

doi = "10.1097/01.gme.0000196593.44335.eb",

language = "English",

volume = "13",

pages = "80--6",

journal = "Menopause",

issn = "1072-3714",

publisher = "Lippincott Williams and Wilkins",

number = "1",

}

TY - JOUR

T1 - Medroxyprogesterone acetate inhibits the cardioprotective effect of estrogen in experimental ischemia-reperfusion injury

AU - Jeanes, Helen L

AU - Wanikiat, Payong

AU - Sharif, Isam

AU - Gray, Gillian A

PY - 2006

Y1 - 2006

N2 - Results from recent clinical trials of estrogen and progestogen therapy (EPT) suggest that some progestogens may interfere with the cardiovascular benefits of estrogen (E). The aim of this study was to investigate whether medroxyprogesterone acetate (MPA) modifies the protective effect of E in experimental ischemia-reperfusion (IR) injury in vivo and in vitro in the rat.

AB - Results from recent clinical trials of estrogen and progestogen therapy (EPT) suggest that some progestogens may interfere with the cardiovascular benefits of estrogen (E). The aim of this study was to investigate whether medroxyprogesterone acetate (MPA) modifies the protective effect of E in experimental ischemia-reperfusion (IR) injury in vivo and in vitro in the rat.

U2 - 10.1097/01.gme.0000196593.44335.eb

DO - 10.1097/01.gme.0000196593.44335.eb

M3 - Article

C2 - 16607102

SN - 1072-3714

VL - 13

SP - 80

EP - 86

JO - Menopause

JF - Menopause

IS - 1

ER -

Medroxyprogesterone acetate inhibits the cardioprotective effect of estrogen in experimental ischemia-reperfusion injury

Abstract / Description of output

Access to Document

Fingerprint

Cite this