Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts

Delilah Zabaneh; Meena Kumari; Manj Sandhu; Nick Wareham; Nick Wainwright; Theodore Papamarkou; Jemma Hopewell; Robert Clarke; KaWah Li; Jutta Palmen; Philippa J Talmud; Florian Kronenberg; Claudia Lamina; Monika Summerer; Bernhard Paulweber; Jackie Price; Francis Fowkes; Marlene Stewart; Fotios Drenos; Sonia Shah; Tina Shah; Juan-Pablo Casas; Mika Kivimaki; John Whittaker; Aroon D Hingorani; Steve E Humphries

doi:10.1016/j.atherosclerosis.2011.04.015

Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts

Delilah Zabaneh, Meena Kumari, Manj Sandhu, Nick Wareham, Nick Wainwright, Theodore Papamarkou, Jemma Hopewell, Robert Clarke, KaWah Li, Jutta Palmen, Philippa J Talmud, Florian Kronenberg, Claudia Lamina, Monika Summerer, Bernhard Paulweber, Jackie Price, Francis Fowkes, Marlene Stewart, Fotios Drenos, Sonia ShahTina Shah, Juan-Pablo Casas, Mika Kivimaki, John Whittaker, Aroon D Hingorani, Steve E Humphries

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

Both genome-wide association studies and candidate gene studies have reported that the major determinant of plasma levels of the Lipoprotein (a) [Lp(a)] reside within the LPA locus on chromosome 6. We have used data from the HumanCVD BeadChip to explore the contribution of other candidate genes determining Lp(a) levels.

Original language	English
Pages (from-to)	447-51
Number of pages	5
Journal	Atherosclerosis
Volume	217
Issue number	2
DOIs	https://doi.org/10.1016/j.atherosclerosis.2011.04.015
Publication status	Published - 2011

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Zabaneh, D., Kumari, M., Sandhu, M., Wareham, N., Wainwright, N., Papamarkou, T., Hopewell, J., Clarke, R., Li, K., Palmen, J., Talmud, P. J., Kronenberg, F., Lamina, C., Summerer, M., Paulweber, B., Price, J., Fowkes, F., Stewart, M., Drenos, F., ... Humphries, S. E. (2011). Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts. Atherosclerosis, 217(2), 447-51. https://doi.org/10.1016/j.atherosclerosis.2011.04.015

@article{d832a21291e9455bb1a292aff8aacfc9,

title = "Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts",

abstract = "Both genome-wide association studies and candidate gene studies have reported that the major determinant of plasma levels of the Lipoprotein (a) [Lp(a)] reside within the LPA locus on chromosome 6. We have used data from the HumanCVD BeadChip to explore the contribution of other candidate genes determining Lp(a) levels.",

author = "Delilah Zabaneh and Meena Kumari and Manj Sandhu and Nick Wareham and Nick Wainwright and Theodore Papamarkou and Jemma Hopewell and Robert Clarke and KaWah Li and Jutta Palmen and Talmud, {Philippa J} and Florian Kronenberg and Claudia Lamina and Monika Summerer and Bernhard Paulweber and Jackie Price and Francis Fowkes and Marlene Stewart and Fotios Drenos and Sonia Shah and Tina Shah and Juan-Pablo Casas and Mika Kivimaki and John Whittaker and Hingorani, {Aroon D} and Humphries, {Steve E}",

year = "2011",

doi = "10.1016/j.atherosclerosis.2011.04.015",

language = "English",

volume = "217",

pages = "447--51",

journal = "Atherosclerosis",

publisher = "Elsevier Science",

number = "2",

}

Zabaneh, D, Kumari, M, Sandhu, M, Wareham, N, Wainwright, N, Papamarkou, T, Hopewell, J, Clarke, R, Li, K, Palmen, J, Talmud, PJ, Kronenberg, F, Lamina, C, Summerer, M, Paulweber, B, Price, J , Fowkes, F , Stewart, M, Drenos, F, Shah, S, Shah, T, Casas, J-P, Kivimaki, M, Whittaker, J, Hingorani, AD & Humphries, SE 2011, 'Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts', Atherosclerosis, vol. 217, no. 2, pp. 447-51. https://doi.org/10.1016/j.atherosclerosis.2011.04.015

TY - JOUR

T1 - Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts

AU - Zabaneh, Delilah

AU - Kumari, Meena

AU - Sandhu, Manj

AU - Wareham, Nick

AU - Wainwright, Nick

AU - Papamarkou, Theodore

AU - Hopewell, Jemma

AU - Clarke, Robert

AU - Li, KaWah

AU - Palmen, Jutta

AU - Talmud, Philippa J

AU - Kronenberg, Florian

AU - Lamina, Claudia

AU - Summerer, Monika

AU - Paulweber, Bernhard

AU - Price, Jackie

AU - Fowkes, Francis

AU - Stewart, Marlene

AU - Drenos, Fotios

AU - Shah, Sonia

AU - Shah, Tina

AU - Casas, Juan-Pablo

AU - Kivimaki, Mika

AU - Whittaker, John

AU - Hingorani, Aroon D

AU - Humphries, Steve E

PY - 2011

Y1 - 2011

N2 - Both genome-wide association studies and candidate gene studies have reported that the major determinant of plasma levels of the Lipoprotein (a) [Lp(a)] reside within the LPA locus on chromosome 6. We have used data from the HumanCVD BeadChip to explore the contribution of other candidate genes determining Lp(a) levels.

AB - Both genome-wide association studies and candidate gene studies have reported that the major determinant of plasma levels of the Lipoprotein (a) [Lp(a)] reside within the LPA locus on chromosome 6. We have used data from the HumanCVD BeadChip to explore the contribution of other candidate genes determining Lp(a) levels.

U2 - 10.1016/j.atherosclerosis.2011.04.015

DO - 10.1016/j.atherosclerosis.2011.04.015

M3 - Article

C2 - 21592478

VL - 217

SP - 447

EP - 451

JO - Atherosclerosis

JF - Atherosclerosis

IS - 2

ER -

Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts

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