Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts

Delilah Zabaneh, Meena Kumari, Manj Sandhu, Nick Wareham, Nick Wainwright, Theodore Papamarkou, Jemma Hopewell, Robert Clarke, KaWah Li, Jutta Palmen, Philippa J Talmud, Florian Kronenberg, Claudia Lamina, Monika Summerer, Bernhard Paulweber, Jackie Price, Francis Fowkes, Marlene Stewart, Fotios Drenos, Sonia ShahTina Shah, Juan-Pablo Casas, Mika Kivimaki, John Whittaker, Aroon D Hingorani, Steve E Humphries

Research output: Contribution to journalArticlepeer-review

Abstract

Both genome-wide association studies and candidate gene studies have reported that the major determinant of plasma levels of the Lipoprotein (a) [Lp(a)] reside within the LPA locus on chromosome 6. We have used data from the HumanCVD BeadChip to explore the contribution of other candidate genes determining Lp(a) levels.
Original languageEnglish
Pages (from-to)447-51
Number of pages5
JournalAtherosclerosis
Volume217
Issue number2
DOIs
Publication statusPublished - 2011

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