Meta-analysis of genome-wide association for migraine in six population-based European cohorts

Lannie Ligthart; Boukje de Vries; Albert V Smith; M Arfan Ikram; Najaf Amin; Jouke-Jan Hottenga; Stephany C Koelewijn; V Mathijs Kattenberg; Marleen H M de Moor; A Cecile J W Janssens; Yurii S Aulchenko; Ben A Oostra; Eco J C de Geus; Johannes H Smit; Frans G Zitman; André G Uitterlinden; Albert Hofman; Gonneke Willemsen; Dale R Nyholt; Grant W Montgomery; Gisela M Terwindt; Vilmundur Gudnason; Brenda W J H Penninx; Monique Breteler; Michel D Ferrari; Lenore J Launer; Cornelia M van Duijn; Arn M J M van den Maagdenberg; Dorret I Boomsma

doi:10.1038/ejhg.2011.48

Meta-analysis of genome-wide association for migraine in six population-based European cohorts

Lannie Ligthart, Boukje de Vries, Albert V Smith, M Arfan Ikram, Najaf Amin, Jouke-Jan Hottenga, Stephany C Koelewijn, V Mathijs Kattenberg, Marleen H M de Moor, A Cecile J W Janssens, Yurii S Aulchenko, Ben A Oostra, Eco J C de Geus, Johannes H Smit, Frans G Zitman, André G Uitterlinden, Albert Hofman, Gonneke Willemsen, Dale R Nyholt, Grant W MontgomeryGisela M Terwindt, Vilmundur Gudnason, Brenda W J H Penninx, Monique Breteler, Michel D Ferrari, Lenore J Launer, Cornelia M van Duijn, Arn M J M van den Maagdenberg, Dorret I Boomsma

Research output: Contribution to journal › Article › peer-review

Abstract

Migraine is a common neurological disorder with a genetically complex background. This paper describes a meta-analysis of genome-wide association (GWA) studies on migraine, performed by the Dutch-Icelandic migraine genetics (DICE) consortium, which brings together six population-based European migraine cohorts with a total sample size of 10,980 individuals (2446 cases and 8534 controls). A total of 32 SNPs showed marginal evidence for association at a P-value

Original language	English
Pages (from-to)	901-7
Number of pages	7
Journal	European Journal of Human Genetics
Volume	19
Issue number	8
DOIs	https://doi.org/10.1038/ejhg.2011.48
Publication status	Published - Aug 2011

Keywords

Cell Adhesion Molecules
Genetic Predisposition to Disease
Genome-Wide Association Study
Glutamic Acid
Iceland
Migraine Disorders
Nerve Tissue Proteins
Netherlands
Polymorphism, Single Nucleotide
Receptors, Nerve Growth Factor

Access to Document

10.1038/ejhg.2011.48

Meta-analysis of genome-wide association for migraine in six population-based European cohorts
Copyright 2011 Macmillan Publishers Limited This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivative Works 3.0 Unported License.
Final published version, 369 KB

Fingerprint Dive into the research topics of 'Meta-analysis of genome-wide association for migraine in six population-based European cohorts'. Together they form a unique fingerprint.

Cite this

Ligthart, L., de Vries, B., Smith, A. V., Ikram, M. A., Amin, N., Hottenga, J-J., Koelewijn, S. C., Kattenberg, V. M., de Moor, M. H. M., Janssens, A. C. J. W., Aulchenko, Y. S., Oostra, B. A., de Geus, E. J. C., Smit, J. H., Zitman, F. G., Uitterlinden, A. G., Hofman, A., Willemsen, G., Nyholt, D. R., ... Boomsma, D. I. (2011). Meta-analysis of genome-wide association for migraine in six population-based European cohorts. European Journal of Human Genetics, 19(8), 901-7. https://doi.org/10.1038/ejhg.2011.48

Ligthart, Lannie ; de Vries, Boukje ; Smith, Albert V ; Ikram, M Arfan ; Amin, Najaf ; Hottenga, Jouke-Jan ; Koelewijn, Stephany C ; Kattenberg, V Mathijs ; de Moor, Marleen H M ; Janssens, A Cecile J W ; Aulchenko, Yurii S ; Oostra, Ben A ; de Geus, Eco J C ; Smit, Johannes H ; Zitman, Frans G ; Uitterlinden, André G ; Hofman, Albert ; Willemsen, Gonneke ; Nyholt, Dale R ; Montgomery, Grant W ; Terwindt, Gisela M ; Gudnason, Vilmundur ; Penninx, Brenda W J H ; Breteler, Monique ; Ferrari, Michel D ; Launer, Lenore J ; van Duijn, Cornelia M ; van den Maagdenberg, Arn M J M ; Boomsma, Dorret I. / Meta-analysis of genome-wide association for migraine in six population-based European cohorts. In: European Journal of Human Genetics. 2011 ; Vol. 19, No. 8. pp. 901-7.

@article{492df57a9c0e4e7d85a3b6b915fd7dbe,

title = "Meta-analysis of genome-wide association for migraine in six population-based European cohorts",

abstract = "Migraine is a common neurological disorder with a genetically complex background. This paper describes a meta-analysis of genome-wide association (GWA) studies on migraine, performed by the Dutch-Icelandic migraine genetics (DICE) consortium, which brings together six population-based European migraine cohorts with a total sample size of 10,980 individuals (2446 cases and 8534 controls). A total of 32 SNPs showed marginal evidence for association at a P-value",

keywords = "Cell Adhesion Molecules, Genetic Predisposition to Disease, Genome-Wide Association Study, Glutamic Acid, Iceland, Migraine Disorders, Nerve Tissue Proteins, Netherlands, Polymorphism, Single Nucleotide, Receptors, Nerve Growth Factor",

author = "Lannie Ligthart and {de Vries}, Boukje and Smith, {Albert V} and Ikram, {M Arfan} and Najaf Amin and Jouke-Jan Hottenga and Koelewijn, {Stephany C} and Kattenberg, {V Mathijs} and {de Moor}, {Marleen H M} and Janssens, {A Cecile J W} and Aulchenko, {Yurii S} and Oostra, {Ben A} and {de Geus}, {Eco J C} and Smit, {Johannes H} and Zitman, {Frans G} and Uitterlinden, {Andr{\'e} G} and Albert Hofman and Gonneke Willemsen and Nyholt, {Dale R} and Montgomery, {Grant W} and Terwindt, {Gisela M} and Vilmundur Gudnason and Penninx, {Brenda W J H} and Monique Breteler and Ferrari, {Michel D} and Launer, {Lenore J} and {van Duijn}, {Cornelia M} and {van den Maagdenberg}, {Arn M J M} and Boomsma, {Dorret I}",

year = "2011",

month = aug,

doi = "10.1038/ejhg.2011.48",

language = "English",

volume = "19",

pages = "901--7",

journal = "European Journal of Human Genetics",

issn = "1018-4813",

publisher = "Springer Nature",

number = "8",

}

Ligthart, L, de Vries, B, Smith, AV, Ikram, MA, Amin, N, Hottenga, J-J, Koelewijn, SC, Kattenberg, VM, de Moor, MHM, Janssens, ACJW, Aulchenko, YS, Oostra, BA, de Geus, EJC, Smit, JH, Zitman, FG, Uitterlinden, AG, Hofman, A, Willemsen, G, Nyholt, DR, Montgomery, GW, Terwindt, GM, Gudnason, V, Penninx, BWJH, Breteler, M, Ferrari, MD, Launer, LJ, van Duijn, CM, van den Maagdenberg, AMJM & Boomsma, DI 2011, 'Meta-analysis of genome-wide association for migraine in six population-based European cohorts', European Journal of Human Genetics, vol. 19, no. 8, pp. 901-7. https://doi.org/10.1038/ejhg.2011.48

Meta-analysis of genome-wide association for migraine in six population-based European cohorts. / Ligthart, Lannie; de Vries, Boukje; Smith, Albert V; Ikram, M Arfan; Amin, Najaf; Hottenga, Jouke-Jan; Koelewijn, Stephany C; Kattenberg, V Mathijs; de Moor, Marleen H M; Janssens, A Cecile J W; Aulchenko, Yurii S; Oostra, Ben A; de Geus, Eco J C; Smit, Johannes H; Zitman, Frans G; Uitterlinden, André G; Hofman, Albert; Willemsen, Gonneke; Nyholt, Dale R; Montgomery, Grant W; Terwindt, Gisela M; Gudnason, Vilmundur; Penninx, Brenda W J H; Breteler, Monique; Ferrari, Michel D; Launer, Lenore J; van Duijn, Cornelia M; van den Maagdenberg, Arn M J M; Boomsma, Dorret I.

In: European Journal of Human Genetics, Vol. 19, No. 8, 08.2011, p. 901-7.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Meta-analysis of genome-wide association for migraine in six population-based European cohorts

AU - Ligthart, Lannie

AU - de Vries, Boukje

AU - Smith, Albert V

AU - Ikram, M Arfan

AU - Amin, Najaf

AU - Hottenga, Jouke-Jan

AU - Koelewijn, Stephany C

AU - Kattenberg, V Mathijs

AU - de Moor, Marleen H M

AU - Janssens, A Cecile J W

AU - Aulchenko, Yurii S

AU - Oostra, Ben A

AU - de Geus, Eco J C

AU - Smit, Johannes H

AU - Zitman, Frans G

AU - Uitterlinden, André G

AU - Hofman, Albert

AU - Willemsen, Gonneke

AU - Nyholt, Dale R

AU - Montgomery, Grant W

AU - Terwindt, Gisela M

AU - Gudnason, Vilmundur

AU - Penninx, Brenda W J H

AU - Breteler, Monique

AU - Ferrari, Michel D

AU - Launer, Lenore J

AU - van Duijn, Cornelia M

AU - van den Maagdenberg, Arn M J M

AU - Boomsma, Dorret I

PY - 2011/8

Y1 - 2011/8

N2 - Migraine is a common neurological disorder with a genetically complex background. This paper describes a meta-analysis of genome-wide association (GWA) studies on migraine, performed by the Dutch-Icelandic migraine genetics (DICE) consortium, which brings together six population-based European migraine cohorts with a total sample size of 10,980 individuals (2446 cases and 8534 controls). A total of 32 SNPs showed marginal evidence for association at a P-value

AB - Migraine is a common neurological disorder with a genetically complex background. This paper describes a meta-analysis of genome-wide association (GWA) studies on migraine, performed by the Dutch-Icelandic migraine genetics (DICE) consortium, which brings together six population-based European migraine cohorts with a total sample size of 10,980 individuals (2446 cases and 8534 controls). A total of 32 SNPs showed marginal evidence for association at a P-value

KW - Cell Adhesion Molecules

KW - Genetic Predisposition to Disease

KW - Genome-Wide Association Study

KW - Glutamic Acid

KW - Iceland

KW - Migraine Disorders

KW - Nerve Tissue Proteins

KW - Netherlands

KW - Polymorphism, Single Nucleotide

KW - Receptors, Nerve Growth Factor

U2 - 10.1038/ejhg.2011.48

DO - 10.1038/ejhg.2011.48

M3 - Article

C2 - 21448238

VL - 19

SP - 901

EP - 907

JO - European Journal of Human Genetics

JF - European Journal of Human Genetics

SN - 1018-4813

IS - 8

ER -