Methods for Precisely Localised Transfer of Cells or DNA into Early Postimplantation Mouse Embryos

Yali Huang, Ron Wilkie, Valerie Wilson

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

We demonstrate a method for grafting cultured cells into defined sites of early mouse embryos to determine their in vivo potential. We also introduce an optimized electroporation method that uses glass capillaries of known diameter, allowing the precise delivery of exogenous DNA into a few cells in the embryos.
Original languageEnglish
Article numbere53295
JournalJournal of Visualized Experiments (JoVE)
Issue number106
DOIs
Publication statusPublished - 25 Dec 2015

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