Methods for producing hepatocytes

Hay DC, Cameron K, Forbes SJ, Ericsson J, Sivertsson L, Rashidi H (Inventor)

Research output: Patent

Abstract

Methods for producing hepatocytes from pluripotent human stem cells are disclosed herein. The stem cells are plated on a cell culture substrate comprising two laminins. The stem cells are then exposed to different cell culture mediums to induce differentiation. The resulting hepatocytes have higher metabolic capacity compared to hepatocytes cultured on different substrates.
Original languageEnglish
Patent numberWO2017072580A1
Publication statusPublished - 4 May 2017

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