Methylome-wide association study of antidepressant use in Generation Scotland and the Netherlands Twin Register implicates the innate immune system

Miruna Carmen Barbu; Floris Huider; Archie Campbell; Carmen Amador; Mark James Adams; Mary-Ellen Lynall; David Howard; Rosie Walker; Stewart Morris; Jenny van Dongen; David John Porteous; Kathryn Louise Evans; Edward Bullmore; Gonneke Willemsen; Dorret Boomsma; Heather Whalley; Andrew M McIntosh

doi:10.1038/s41380-021-01412-7

Methylome-wide association study of antidepressant use in Generation Scotland and the Netherlands Twin Register implicates the innate immune system

Miruna Carmen Barbu, Floris Huider, Archie Campbell, Carmen Amador, Mark James Adams, Mary-Ellen Lynall, David Howard, Rosie Walker, Stewart Morris, Jenny van Dongen, David John Porteous, Kathryn Louise Evans, Edward Bullmore, Gonneke Willemsen, Dorret Boomsma, Heather Whalley, Andrew M McIntosh

Research output: Contribution to journal › Article › peer-review

Original language	English
Journal	Molecular Psychiatry
Early online date	8 Dec 2021
DOIs	https://doi.org/10.1038/s41380-021-01412-7
Publication status	E-pub ahead of print - 8 Dec 2021

Keywords / Materials (for Non-textual outputs)

DNA methylation
methylome-wide association study
methylation-based score
innate immune system
major depressive disorder
antidepressant use

Access to Document

10.1038/s41380-021-01412-7Licence: Creative Commons: Attribution (CC-BY)

s41380-021-01412-7Final published version, 1.78 MBLicence: Creative Commons: Attribution (CC-BY)

https://www.nature.com/articles/s41380-021-01412-7.pdfLicence: Creative Commons: Attribution (CC-BY)

1 Oral presentation
1 Research and Teaching at External Organisation

23andme, Inc, Sunnyvale, California
Andrew McIntosh (Chair)
4 Oct 2023
Activity: Visiting an external institution types › Research and Teaching at External Organisation
Key insights from genomic studies of depression
Andrew McIntosh (Assessor)
19 Jan 2023
Activity: Academic talk or presentation types › Oral presentation

Cite this

Barbu, M. C., Huider, F., Campbell, A., Amador, C., Adams, M. J., Lynall, M.-E., Howard, D., Walker, R., Morris, S., van Dongen, J., Porteous, D. J., Evans, K. L., Bullmore, E., Willemsen, G., Boomsma, D., Whalley, H., & McIntosh, A. M. (2021). Methylome-wide association study of antidepressant use in Generation Scotland and the Netherlands Twin Register implicates the innate immune system. Molecular Psychiatry. Advance online publication. https://doi.org/10.1038/s41380-021-01412-7

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title = "Methylome-wide association study of antidepressant use in Generation Scotland and the Netherlands Twin Register implicates the innate immune system",

keywords = "DNA methylation, methylome-wide association study, methylation-based score, innate immune system, major depressive disorder, antidepressant use",

author = "Barbu, {Miruna Carmen} and Floris Huider and Archie Campbell and Carmen Amador and Adams, {Mark James} and Mary-Ellen Lynall and David Howard and Rosie Walker and Stewart Morris and {van Dongen}, Jenny and Porteous, {David John} and Evans, {Kathryn Louise} and Edward Bullmore and Gonneke Willemsen and Dorret Boomsma and Heather Whalley and McIntosh, {Andrew M}",

year = "2021",

month = dec,

day = "8",

doi = "10.1038/s41380-021-01412-7",

language = "English",

journal = "Molecular Psychiatry",

issn = "1359-4184",

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Barbu, MC, Huider, F, Campbell, A, Amador, C, Adams, MJ, Lynall, M-E, Howard, D, Walker, R, Morris, S, van Dongen, J, Porteous, DJ, Evans, KL, Bullmore, E, Willemsen, G, Boomsma, D, Whalley, H & McIntosh, AM 2021, 'Methylome-wide association study of antidepressant use in Generation Scotland and the Netherlands Twin Register implicates the innate immune system', Molecular Psychiatry. https://doi.org/10.1038/s41380-021-01412-7

TY - JOUR

T1 - Methylome-wide association study of antidepressant use in Generation Scotland and the Netherlands Twin Register implicates the innate immune system

AU - Barbu, Miruna Carmen

AU - Huider, Floris

AU - Campbell, Archie

AU - Amador, Carmen

AU - Adams, Mark James

AU - Lynall, Mary-Ellen

AU - Howard, David

AU - Walker, Rosie

AU - Morris, Stewart

AU - van Dongen, Jenny

AU - Porteous, David John

AU - Evans, Kathryn Louise

AU - Bullmore, Edward

AU - Willemsen, Gonneke

AU - Boomsma, Dorret

AU - Whalley, Heather

AU - McIntosh, Andrew M

PY - 2021/12/8

Y1 - 2021/12/8

KW - DNA methylation

KW - methylome-wide association study

KW - methylation-based score

KW - innate immune system

KW - major depressive disorder

KW - antidepressant use

U2 - 10.1038/s41380-021-01412-7

DO - 10.1038/s41380-021-01412-7

M3 - Article

SN - 1359-4184

JO - Molecular Psychiatry

JF - Molecular Psychiatry

ER -

Methylome-wide association study of antidepressant use in Generation Scotland and the Netherlands Twin Register implicates the innate immune system

Keywords / Materials (for Non-textual outputs)

Access to Document

Activities

23andme, Inc, Sunnyvale, California

Key insights from genomic studies of depression

Cite this