Microarray platforms for enzymatic and cell-based assays

Juan J. Diaz-Mochon, Guilhem Tourniaire, Mark Bradley

Research output: Contribution to journalLiterature reviewpeer-review

Abstract

This tutorial review introduces the uninitiated to the world of microarrays (or so-called chips) and covers a number of basic concepts such as substrates and surfaces, printing and analysis. It then moves on to look at some newer applications of microarray technology, which include enzyme analysis (notably kinases and proteases) as well as the growing enchantment with so-called cell-based microarrays that offer a unique approach to high-throughput cellular analysis. Finally, it looks forwards and highlights future possible trends and directions in the microarray arena.

Original languageEnglish
Pages (from-to)449-457
Number of pages9
JournalChemical Society Reviews
Volume36
Issue number3
DOIs
Publication statusPublished - 2007

Keywords

  • EMBRYONIC STEM-CELLS
  • SUBSTRATE-SPECIFICITY
  • PEPTIDE MICROARRAYS
  • PROTEIN MICROARRAYS
  • KINASE-ACTIVITY
  • ARRAY
  • DNA
  • DIFFERENTIATION
  • IDENTIFICATION
  • TECHNOLOGY

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