Microarrays of peptide fibrils created by electrostatically controlled deposition

P Mesquida, D L Ammann, C E MacPhee, R A McKendry, Cait MacPhee

Research output: Contribution to journalArticlepeer-review

Abstract

The adsorption of beta-sheet-rich fibrils produced in vitro via the self-assembly of polypeptides onto surfaces is found to be governed by electrostatic interactions. Chemically patterned substrates are used to create lateral micropatterns of fibrils and hybrid microstructures of fibrils with inorganic nanoparticles (see Figure). beta-sheet-rich fibrils are promising as functional biomaterials.

Original languageEnglish
Pages (from-to)893-+
Number of pages6
JournalAdvanced Materials
Volume17
Issue number7
DOIs
Publication statusPublished - 4 Apr 2005

Keywords

  • AMYLOID FIBRIL
  • NANOWIRES

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