Prion diseases are infectious protein-misfolding disorders associated with neurodegeneration and glial activation in the CNS. Microglia have been suggested to play a critical role during prion disease. Mice deficient in microglia Csf1rΔFIRE develop normally. We challenged these mice with infectious prions in order to understand the role of microglia during neurodegeneration.
|Publication status||Published - 11 Mar 2020|
|Event||Edinburgh Neuroscience: Neuroscience Day - Edinburgh, United Kingdom|
Duration: 17 Mar 2009 → …
|Conference||Edinburgh Neuroscience: Neuroscience Day|
|Period||17/03/09 → …|