Abstract / Description of output
Prion diseases are infectious protein-misfolding disorders associated with neurodegeneration and glial activation in the CNS. Microglia have been suggested to play a critical role during prion disease. Mice deficient in microglia Csf1rΔFIRE develop normally. We challenged these mice with infectious prions in order to understand the role of microglia during neurodegeneration.
Original language | English |
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Publication status | Published - 11 Mar 2020 |
Event | Edinburgh Neuroscience: Neuroscience Day - Edinburgh, United Kingdom Duration: 17 Mar 2009 → … |
Conference
Conference | Edinburgh Neuroscience: Neuroscience Day |
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Country/Territory | United Kingdom |
City | Edinburgh |
Period | 17/03/09 → … |