miRNAs in development and pathogenesis of the nervous system

Jakub S Nowak; Gracjan Michlewski

doi:10.1042/BST20130044

miRNAs in development and pathogenesis of the nervous system

Jakub S Nowak, Gracjan Michlewski

School of Biological Sciences

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

The human nervous system expresses approximately 70% of all miRNAs (microRNAs). Changing levels of certain ubiquitous and brain-specific miRNAs shape the development and function of the nervous system. It is becoming clear that misexpression of some miRNAs can contribute towards neurodevelopmental disorders. In the present article, we review the current knowledge of the role of miRNAs in development and pathogenesis of the nervous system.

Original language	English
Pages (from-to)	815-820
Number of pages	6
Journal	Biochemical Society Transactions
Volume	41
Issue number	4
DOIs	https://doi.org/10.1042/BST20130044
Publication status	Published - 18 Jul 2013

Keywords / Materials (for Non-textual outputs)

microRNA (miRNA)
microRNA biogenesis
nervous system
neuropathogenesis
synaptic plasticity

Access to Document

10.1042/BST20130044

Cite this

@article{9d2c07fe70fb433caf97ce9b9f262300,

title = "miRNAs in development and pathogenesis of the nervous system",

abstract = "The human nervous system expresses approximately 70% of all miRNAs (microRNAs). Changing levels of certain ubiquitous and brain-specific miRNAs shape the development and function of the nervous system. It is becoming clear that misexpression of some miRNAs can contribute towards neurodevelopmental disorders. In the present article, we review the current knowledge of the role of miRNAs in development and pathogenesis of the nervous system.",

keywords = "microRNA (miRNA), microRNA biogenesis, nervous system, neuropathogenesis, synaptic plasticity",

author = "Nowak, {Jakub S} and Gracjan Michlewski",

year = "2013",

month = jul,

day = "18",

doi = "10.1042/BST20130044",

language = "English",

volume = "41",

pages = "815--820",

journal = "Biochemical Society Transactions",

issn = "0300-5127",

publisher = "Portland Press Ltd.",

number = "4",

}

TY - JOUR

T1 - miRNAs in development and pathogenesis of the nervous system

AU - Nowak, Jakub S

AU - Michlewski, Gracjan

PY - 2013/7/18

Y1 - 2013/7/18

N2 - The human nervous system expresses approximately 70% of all miRNAs (microRNAs). Changing levels of certain ubiquitous and brain-specific miRNAs shape the development and function of the nervous system. It is becoming clear that misexpression of some miRNAs can contribute towards neurodevelopmental disorders. In the present article, we review the current knowledge of the role of miRNAs in development and pathogenesis of the nervous system.

AB - The human nervous system expresses approximately 70% of all miRNAs (microRNAs). Changing levels of certain ubiquitous and brain-specific miRNAs shape the development and function of the nervous system. It is becoming clear that misexpression of some miRNAs can contribute towards neurodevelopmental disorders. In the present article, we review the current knowledge of the role of miRNAs in development and pathogenesis of the nervous system.

KW - microRNA (miRNA)

KW - microRNA biogenesis

KW - nervous system

KW - neuropathogenesis

KW - synaptic plasticity

U2 - 10.1042/BST20130044

DO - 10.1042/BST20130044

M3 - Article

C2 - 23863137

SN - 0300-5127

VL - 41

SP - 815

EP - 820

JO - Biochemical Society Transactions

JF - Biochemical Society Transactions

IS - 4

ER -

miRNAs in development and pathogenesis of the nervous system

Abstract / Description of output

Keywords / Materials (for Non-textual outputs)

Access to Document

Fingerprint

Cite this