Model reduction for stochastic reaction systems

Stephen Smith, Ramon Grima*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

It is often the case that one or more species in a system are much more abundant than the rest of the species. For such cases solving or simulating the master equation of the whole system is unnecessary since only the less abundant species will exhibit significant fluctuations number of fluctuations. Here we present a simple technique by which one can obtain, from the master equation of the full system, a reduced master equation for the less abundant species only. The method is illustrated on various examples drawn from chemistry, molecular biology and ecology.

Original languageEnglish
Title of host publicationStochastic Processes, Multiscale Modeling, and Numerical Methods for Computational Cellular Biology
PublisherSpringer International Publishing Switzerland
Pages143-158
Number of pages16
ISBN (Electronic)9783319626277
ISBN (Print)9783319626260
DOIs
Publication statusE-pub ahead of print - 5 Oct 2017

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