Modelling phase precession in the hippocampus

Angus Chadwick; Mark van Rossum; Matthew Nolan

doi:10.1186/1471-2202-16-S1-O18

Modelling phase precession in the hippocampus

Angus Chadwick, Mark van Rossum, Matthew Nolan

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

The activity of cells in the rodent hippocampus is strongly modulated by both the location of the animal and the ongoing theta oscillation. Place cells, but not interneurons, show a strong spatial modulation of their firing rates, while both place cells and interneurons exhibit phase precession, a phenomenon whereby they spike at a faster frequency than the LFP theta oscillation, causing their spikes to shift to an earlier phase of this rhythm on each successive cycle [1-3]. Despite extensive research into this phenomenon, the mechanisms underlying phase precession remain unclear.

Original language	English
Article number	O18
Number of pages	2
Journal	BMC Neuroscience
Volume	16
Issue number	Suppl 1
DOIs	https://doi.org/10.1186/1471-2202-16-S1-O18
Publication status	Published - 15 Dec 2015
Event	24th Annual Computational Neuroscience Meeting - Prague, Czech Republic Duration: 18 Jul 2015 → 23 Jul 2015 Conference number: 24 https://www.cnsorg.org/past-annual-meetings

Keywords / Materials (for Non-textual outputs)

Open Environment
Place Cell
Medial Septum
Place Field
Head Direction

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10.1186/1471-2202-16-S1-O18Licence: Creative Commons: Attribution (CC-BY)

Modelling Phase Precession_CHADWICK_DOA18032020_VOR_CC-BYFinal published version, 205 KBLicence: Creative Commons: Attribution (CC-BY)

https://link.springer.com/article/10.1186/1471-2202-16-S1-O18Licence: Creative Commons: Attribution (CC-BY)

Cite this

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title = "Modelling phase precession in the hippocampus",

abstract = "The activity of cells in the rodent hippocampus is strongly modulated by both the location of the animal and the ongoing theta oscillation. Place cells, but not interneurons, show a strong spatial modulation of their firing rates, while both place cells and interneurons exhibit phase precession, a phenomenon whereby they spike at a faster frequency than the LFP theta oscillation, causing their spikes to shift to an earlier phase of this rhythm on each successive cycle [1-3]. Despite extensive research into this phenomenon, the mechanisms underlying phase precession remain unclear.",

keywords = "Open Environment, Place Cell, Medial Septum, Place Field, Head Direction",

author = "Angus Chadwick and {van Rossum}, Mark and Matthew Nolan",

year = "2015",

month = dec,

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doi = "10.1186/1471-2202-16-S1-O18",

language = "English",

volume = "16",

journal = "BMC Neuroscience",

issn = "1471-2202",

publisher = "BioMed Central",

number = "Suppl 1",

note = "24th Annual Computational Neuroscience Meeting, CNS 2015 ; Conference date: 18-07-2015 Through 23-07-2015",

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TY - JOUR

T1 - Modelling phase precession in the hippocampus

AU - Chadwick, Angus

AU - van Rossum, Mark

AU - Nolan, Matthew

N1 - Conference code: 24

PY - 2015/12/15

Y1 - 2015/12/15

N2 - The activity of cells in the rodent hippocampus is strongly modulated by both the location of the animal and the ongoing theta oscillation. Place cells, but not interneurons, show a strong spatial modulation of their firing rates, while both place cells and interneurons exhibit phase precession, a phenomenon whereby they spike at a faster frequency than the LFP theta oscillation, causing their spikes to shift to an earlier phase of this rhythm on each successive cycle [1-3]. Despite extensive research into this phenomenon, the mechanisms underlying phase precession remain unclear.

AB - The activity of cells in the rodent hippocampus is strongly modulated by both the location of the animal and the ongoing theta oscillation. Place cells, but not interneurons, show a strong spatial modulation of their firing rates, while both place cells and interneurons exhibit phase precession, a phenomenon whereby they spike at a faster frequency than the LFP theta oscillation, causing their spikes to shift to an earlier phase of this rhythm on each successive cycle [1-3]. Despite extensive research into this phenomenon, the mechanisms underlying phase precession remain unclear.

KW - Open Environment

KW - Place Cell

KW - Medial Septum

KW - Place Field

KW - Head Direction

U2 - 10.1186/1471-2202-16-S1-O18

DO - 10.1186/1471-2202-16-S1-O18

M3 - Article

SN - 1471-2202

VL - 16

JO - BMC Neuroscience

JF - BMC Neuroscience

IS - Suppl 1

M1 - O18

T2 - 24th Annual Computational Neuroscience Meeting

Y2 - 18 July 2015 through 23 July 2015

ER -

Modelling phase precession in the hippocampus

Abstract / Description of output

Keywords / Materials (for Non-textual outputs)

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Cite this