Abstract
The representation of liquid-liquid equilibria (LLE) in ternary systems composed by water, 1,4-dioxane and different grades of poly(lactic acid) (PDLLA and PLLA), has been addressed through the PC-SAFT equation of state (EoS), in which the scheme of induced association is used to represent the interaction between solvent (dioxane) and non-solvent (water). The model parameters devoted to the description of pure component properties, as well as those pertinent to the representation of thermodynamic behaviour of solvent/non-solvent mixtures, were tuned on the basis of specific pressure-volume-temperature (PVT) data for the corresponding systems. Only the binary parameters for polymer-solvent and polymer/non-solvent pairs were adjusted to obtain a useful representation of experimental LLE data for the ternary systems. A suitable description of the thermodynamic properties of ternary mixtures was obtained using temperature-independent binary interaction parameters in the range 25-80. °C, and the consistency of the approach in the entire composition range was verified against experimental solubility data specifically measured for the polymer/non-solvent pair. The model shows good ability in the description of the thermodynamic properties of the system and it represents a reliable tool for the prediction of LLE also at conditions different from those considered for its set-up. This approach thus represents a useful designing tool for processes, such as thermally induced phase separation (TIPS), used in the preparation of microporous polymeric scaffolds. © 2014 Elsevier B.V.
Original language | English |
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Pages (from-to) | 1-8 |
Number of pages | 8 |
Journal | Fluid phase equilibria |
Volume | 374 |
DOIs | |
Publication status | Published - 2014 |
Keywords
- Association reactions
- Equations of state
- Ethers
- Mixtures
- Phase equilibria
- Phase separation
- Polymers
- Polyols
- Scaffolds
- Solvents
- Ternary systems
- Thermodynamic properties
- Tools
- Binary interaction parameter
- Experimental solubility datum
- Liquid liquid equilibrium
- Liquid-liquid-equilibria
- PC-SAFT
- Pressure-volume-temperatures
- Thermally induced phase separation
- TIPS
- Scaffolds (biology)