Modelling the epidemiology and transmission of Verocytotoxin-producing Escherichia coli serogroups O26 and O103 in two different calf cohorts

W-C Liu; D J Shaw; L Matthews; Deborah Hoyle; M C Pearce; C M Yates; J C Low; S G B Amyes; G J Gunn; M E J Woolhouse

doi:10.1017/S0950268806007722

Modelling the epidemiology and transmission of Verocytotoxin-producing Escherichia coli serogroups O26 and O103 in two different calf cohorts

W-C Liu, D J Shaw, L Matthews, Deborah Hoyle, M C Pearce, C M Yates, J C Low, S G B Amyes, G J Gunn, M E J Woolhouse

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

Mathematical models are constructed to investigate the population dynamics of Verocytotoxin-producing Escherichia coli (VTEC) serogroups O26 and O103 in two different calf cohorts. We compare the epidemiological characteristics of these two serogroups within the same calf cohort as well as the same serogroups between the two calf cohorts. The sources of infection are quantified for both calf cohort studies. VTEC serogroups O26 and O103 mainly differ in the rate at which calves acquire infection from sources other than infected calves, while infected calves typically remain infectious for less than 1 week regardless of the serogroups. Fewer than 20% of VTEC-positive samples are the result of calf-to-calf transmission. PFGE typing data are available for VTEC-positive samples to further subdivide the serogroup data in one of the two calf cohort studies. For serogroup O26 but not O103, there is evidence for unequal environmental exposure to infection with different PFGE types.

Original language	English
Pages (from-to)	1316-23
Number of pages	8
Journal	Epidemiology & Infection
Volume	135
Issue number	8
DOIs	https://doi.org/10.1017/S0950268806007722
Publication status	Published - 2007

Keywords / Materials (for Non-textual outputs)

Animals
CATTLE
cattle disease
Cohort Studies
DNA Fingerprinting
Electrophoresis, Gel, Pulsed-Field
Escherichia coli Infections
Models, Theoretical
MOLECULAR EPIDEMIOLOGY
O Antigens
Serotyping
Shiga-Toxigenic Escherichia coli

Access to Document

10.1017/S0950268806007722

Modelling the epidemiology and transmission of Verocytotoxin-producing Escherichia coli serogroups O26 and O103 in two different calf cohorts.pdf
Copyright 2007 Cambridge University Press
Final published version, 211 KB

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Cite this

Liu, W.-C., Shaw, D. J., Matthews, L., Hoyle, D., Pearce, M. C., Yates, C. M., Low, J. C., Amyes, S. G. B., Gunn, G. J., & Woolhouse, M. E. J. (2007). Modelling the epidemiology and transmission of Verocytotoxin-producing Escherichia coli serogroups O26 and O103 in two different calf cohorts. Epidemiology & Infection, 135(8), 1316-23. https://doi.org/10.1017/S0950268806007722

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abstract = "Mathematical models are constructed to investigate the population dynamics of Verocytotoxin-producing Escherichia coli (VTEC) serogroups O26 and O103 in two different calf cohorts. We compare the epidemiological characteristics of these two serogroups within the same calf cohort as well as the same serogroups between the two calf cohorts. The sources of infection are quantified for both calf cohort studies. VTEC serogroups O26 and O103 mainly differ in the rate at which calves acquire infection from sources other than infected calves, while infected calves typically remain infectious for less than 1 week regardless of the serogroups. Fewer than 20% of VTEC-positive samples are the result of calf-to-calf transmission. PFGE typing data are available for VTEC-positive samples to further subdivide the serogroup data in one of the two calf cohort studies. For serogroup O26 but not O103, there is evidence for unequal environmental exposure to infection with different PFGE types.",

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AB - Mathematical models are constructed to investigate the population dynamics of Verocytotoxin-producing Escherichia coli (VTEC) serogroups O26 and O103 in two different calf cohorts. We compare the epidemiological characteristics of these two serogroups within the same calf cohort as well as the same serogroups between the two calf cohorts. The sources of infection are quantified for both calf cohort studies. VTEC serogroups O26 and O103 mainly differ in the rate at which calves acquire infection from sources other than infected calves, while infected calves typically remain infectious for less than 1 week regardless of the serogroups. Fewer than 20% of VTEC-positive samples are the result of calf-to-calf transmission. PFGE typing data are available for VTEC-positive samples to further subdivide the serogroup data in one of the two calf cohort studies. For serogroup O26 but not O103, there is evidence for unequal environmental exposure to infection with different PFGE types.

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KW - O Antigens

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