Molecular domains of myelinated axons in the peripheral nervous system

James L Salzer, Peter J Brophy, Elior Peles

Research output: Contribution to journalLiterature reviewpeer-review

Abstract / Description of output

Myelinated axons are organized into a series of specialized domains with distinct molecular compositions and functions. These domains, which include the node of Ranvier, the flanking paranodal junctions, the juxtaparanodes, and the internode, form as the result of interactions with myelinating Schwann cells. This domain organization is essential for action potential propagation by saltatory conduction and for the overall function and integrity of the axon.
Original languageEnglish
Pages (from-to)1532-40
Number of pages9
Issue number14
Publication statusPublished - Nov 2008


Dive into the research topics of 'Molecular domains of myelinated axons in the peripheral nervous system'. Together they form a unique fingerprint.

Cite this