Molecular mechanisms of ovarian hyperstimulation syndrome: paracrine reduction of endothelial claudin 5 by hCG in vitro is associated with increased endothelial permeability

M Rodewald, D Herr, W C Duncan, H M Fraser, G Hack, R Konrad, F Gagsteiger, R Kreienberg, C Wulff

Research output: Contribution to journalArticlepeer-review

Abstract

Ovarian hyperstimulation syndrome (OHSS) is a potentially life-threatening complication of ovarian stimulation associated with severe vascular hyperpermeability. Primary co-cultures of human luteinized granulosa cells (LGCs) and human umbilical vein endothelial cells (HUVECs) were used as a model of steroidgenic/endothelial cell interaction in OHSS.
Original languageEnglish
Pages (from-to)1191-9
Number of pages9
JournalHuman Reproduction
Volume24
Issue number5
DOIs
Publication statusPublished - May 2009

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