@inproceedings{b48c3258b7f5445f9e9e73fe5aae04cf,
title = "Molecules for memory: modelling CaMKII",
abstract = "Long-term modifications of synaptic strength, such as long-term potentiation (LTP) or long-term depression (LTD) are thought to underlie some forms of learning and memory. At the excitatory glutamate synapse, LTP is dependent on calcium influx through the N-methyl-D-aspartate (NMDA) receptor and subsequent activation of calcium/calmodulin-dependent protein kinase II (CaMKII). The NMDA receptor, CaMKII, and its activator calmodulin are all embedded in a complex hyperstructure consisting of more than 180 molecules [1] that acts as as a {"}synaptic plasticity nanomachine{"}. Our current work aims at exploring CaMKII function in the context of the NMDA receptor complex",
keywords = "CaMKII, modelling, synapse",
author = "Melanie Stefan and {Le Nov{\`e}re}, Nicolas",
year = "2007",
month = may,
day = "8",
doi = "10.1186/1752-0509-1-S1-P40",
language = "English",
volume = "1",
series = "BioSysBio 2007: Systems Biology, Bioinformatics, Synthetic Biology",
pages = "P40",
booktitle = "BMC Systems Biology",
edition = "Suppl 1",
note = " BioSysBio 2007: Systems Biology, Bioinformatics, Synthetic Biology ; Conference date: 11-01-2007 Through 13-01-2007",
}