More, more, more: downregulation of a MK5-FoxO3a-mir34b/c pathway further increases c-Myc levels in colorectal cancer

Kevin Myant, Owen J Sansom

Research output: Contribution to journalArticlepeer-review

Abstract

The c-Myc transcription factor has been shown to be central for colorectal carcinogenesis. In this issue of Molecular Cell, Kress and colleagues (Kress et al., 2011) identify an exciting new pathway that downregulates c-Myc translation which is lost in aggressive colorectal cancer.

Original languageEnglish
Pages (from-to)369-70
Number of pages2
JournalMolecular Cell
Volume41
Issue number4
DOIs
Publication statusPublished - 18 Feb 2011

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