Abstract / Description of output
A study has been made of the development of mesonephric tubules in the mouse to investigate the possible transdifferentiation of tubule epithelial cell to gonadal somatic cells and/or adrenal cortical cells. Immunohistochemical localisation of laminin was carried out to study the development of basal laminae. Cells at the ventral aspect of mesonephric tubules did not show an epithelial phenotype during the period of somatic cell population of the gonadal blastema; a basal lamina appeared ventrally only after this period. Therefore, it is not necessary to postulate transdifferentiation of these cells.
| Original language | English |
|---|---|
| Pages (from-to) | 171-84 |
| Number of pages | 14 |
| Journal | Journal of Anatomy |
| Volume | 174 |
| Publication status | Published - Feb 1991 |
Keywords / Materials (for Non-textual outputs)
- Adrenal Cortex
- Animals
- Cell Differentiation
- Female
- Male
- Mesonephros
- Mice
- Mice, Inbred CBA
- Microscopy, Electron
- Ovary
- Testis
- Time Factors