Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlled trial of repurposed drugs in motor neuron disease

Charis Wong; Rachel S Dakin; Jill Williamson; Judith Newton; Michelle Steven; Shuna Colville; Maria Stavrou; Jenna M Gregory; Elizabeth Elliott; Arpan R Mehta; Jeremy Chataway; Robert J Swingler; Richard Anthony Parker; Christopher J Weir; Nigel Stallard; Mahesh K B Parmar; Malcolm R Macleod; Suvankar Pal; Siddharthan Chandran

doi:10.1136/bmjopen-2022-064173

Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlled trial of repurposed drugs in motor neuron disease

Charis Wong, Rachel S Dakin, Jill Williamson, Judith Newton, Michelle Steven, Shuna Colville, Maria Stavrou, Jenna M Gregory, Elizabeth Elliott, Arpan R Mehta, Jeremy Chataway, Robert J Swingler, Richard Anthony Parker, Christopher J Weir, Nigel Stallard, Mahesh K B Parmar, Malcolm R Macleod, Suvankar Pal, Siddharthan Chandran

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	e064173
Journal	BMJ Open
Volume	12
Issue number	7
DOIs	https://doi.org/10.1136/bmjopen-2022-064173
Publication status	Published - 7 Jul 2022

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10.1136/bmjopen-2022-064173

e064173_MND-SMART.fullFinal published version, 1.36 MBLicence: Creative Commons: Attribution (CC-BY)

https://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2022-064173

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Wong, C., Dakin, R. S., Williamson, J., Newton, J., Steven, M., Colville, S., Stavrou, M., Gregory, J. M., Elliott, E., Mehta, A. R., Chataway, J., Swingler, R. J., Parker, R. A., Weir, C. J., Stallard, N., Parmar, M. K. B., Macleod, M. R., Pal, S., & Chandran, S. (2022). Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlled trial of repurposed drugs in motor neuron disease. BMJ Open, 12(7), e064173. https://doi.org/10.1136/bmjopen-2022-064173

@article{502df870dcdf466e8a6b1f582de31bbe,

title = "Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlled trial of repurposed drugs in motor neuron disease",

author = "Charis Wong and Dakin, {Rachel S} and Jill Williamson and Judith Newton and Michelle Steven and Shuna Colville and Maria Stavrou and Gregory, {Jenna M} and Elizabeth Elliott and Mehta, {Arpan R} and Jeremy Chataway and Swingler, {Robert J} and Parker, {Richard Anthony} and Weir, {Christopher J} and Nigel Stallard and Parmar, {Mahesh K B} and Macleod, {Malcolm R} and Suvankar Pal and Siddharthan Chandran",

note = "Publisher Copyright: {\textcopyright} Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ.",

year = "2022",

month = jul,

day = "7",

doi = "10.1136/bmjopen-2022-064173",

language = "English",

volume = "12",

pages = "e064173",

journal = "BMJ Open",

issn = "2044-6055",

publisher = "BMJ Publishing Group",

number = "7",

}

Wong, C, Dakin, RS, Williamson, J, Newton, J, Steven, M, Colville, S, Stavrou, M, Gregory, JM, Elliott, E, Mehta, AR, Chataway, J, Swingler, RJ, Parker, RA , Weir, CJ, Stallard, N, Parmar, MKB, Macleod, MR , Pal, S & Chandran, S 2022, 'Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlled trial of repurposed drugs in motor neuron disease', BMJ Open, vol. 12, no. 7, pp. e064173. https://doi.org/10.1136/bmjopen-2022-064173

Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlled trial of repurposed drugs in motor neuron disease. / Wong, Charis; Dakin, Rachel S; Williamson, Jill et al.
In: BMJ Open, Vol. 12, No. 7, 07.07.2022, p. e064173.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlled trial of repurposed drugs in motor neuron disease

AU - Wong, Charis

AU - Dakin, Rachel S

AU - Williamson, Jill

AU - Newton, Judith

AU - Steven, Michelle

AU - Colville, Shuna

AU - Stavrou, Maria

AU - Gregory, Jenna M

AU - Elliott, Elizabeth

AU - Mehta, Arpan R

AU - Chataway, Jeremy

AU - Swingler, Robert J

AU - Parker, Richard Anthony

AU - Weir, Christopher J

AU - Stallard, Nigel

AU - Parmar, Mahesh K B

AU - Macleod, Malcolm R

AU - Pal, Suvankar

AU - Chandran, Siddharthan

PY - 2022/7/7

Y1 - 2022/7/7

U2 - 10.1136/bmjopen-2022-064173

DO - 10.1136/bmjopen-2022-064173

M3 - Article

SN - 2044-6055

VL - 12

SP - e064173

JO - BMJ Open

JF - BMJ Open

IS - 7

ER -

Wong C, Dakin RS, Williamson J, Newton J, Steven M, Colville S et al. Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlled trial of repurposed drugs in motor neuron disease. BMJ Open. 2022 Jul 7;12(7):e064173. doi: 10.1136/bmjopen-2022-064173