Mouse models of cystic fibrosis

D J Davidson, M Rolfe

Research output: Contribution to journalArticlepeer-review

Abstract

The development of mouse models for cystic fibrosis has provided the opportunity to dissect disease pathogenesis, correlate genotype and phenotype, study disease-modifying genes and develop novel therapeutics. This review discusses the successes and the challenges encountered in characterizing and optimizing these models.

Original languageEnglish
Pages (from-to)S29-37
JournalTrends in Genetics
Volume17
Issue number10
Publication statusPublished - Oct 2001

Keywords

  • Animals
  • Cystic Fibrosis
  • Disease Models, Animal
  • Humans
  • Intestinal Diseases
  • Lung Diseases
  • Mice
  • Mice, Mutant Strains
  • Pancreatic Diseases
  • Phenotype

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