MRI of the optic nerve sheath and globe in cats with and without presumed intracranial hypertension

Joanna Lodzinska, Elizabeth Munro, Darren Shaw, Anna Sunol Iniesta

Research output: Contribution to journalArticlepeer-review

Abstract

OBJECTIVES: The study aimed to: 1) test MRI repeatability of measurements of optic nerve sheath diameter (ONSD), optic nerve diameter (OND), and globe transverse diameter (ETD); 2) study the associations between the OND, ONSD and ETD; 3) assess if these measurements are affected by age or body weight; and 4) test the association between ONSD, OND, ETD and ONSD/ETD ratio with presumed intracranial pressure (ICP) status.
METHODS: Retrospective and blinded study where patients were allocated to presumed normal or intracranial hypertension groups based on MRI findings. The ONSD and ETD were measured and recorded. Interclass correlation coefficient (ICC) was calculated to investigate the interobserver agreement. Data were analyzed using Pearson correlation coefficient, two sample t-test and general linear model ANOVA.
RESULTS: Seventy-seven cats were included with 62 patients in presumed normal, and 15 in presumed intracranial hypertension group. The ICC showed moderate to good reliability for all measurements. Positive correlations were identified for: 1) ETD and weight; 2) ONSD and age; 3) OND and age; 4) ONSD and ETD; 5) ONSD/ETD ratio and presumed ICP status; and 6) ONSD and presumed ICP status. No difference was detected between the presumed
Original languageEnglish
JournalJournal of Feline Medicine and Surgery
DOIs
Publication statusPublished - 30 Nov 2020

Keywords

  • brain
  • cranial nerve II
  • Cushing's reflex
  • intracranial Hypertension
  • neurology
  • magnetic resonance imaging

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