mRNA stability in eukaryotes

P Mitchell, D Tollervey

Research output: Contribution to journalArticlepeer-review

Abstract

During the past two years, the role of the proteins HuR and hnRNP D in regulated mRNA degradation in humans has become clearer, and a putative mRNA deadenylase, DAN or PARN, has been identified. In yeast, the relationship between translation and mRNA turnover is clearer, but the mRNA decapping process has turned out to be unexpectedly complex.

Original languageEnglish
Pages (from-to)193-198
Number of pages6
JournalCurrent Opinion in Genetics and Development
Volume10
Issue number2
DOIs
Publication statusPublished - 1 Apr 2000

Keywords

  • genetics

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