MRNA turnover

D Tollervey, Philip Mitchell

Research output: Contribution to journalLiterature reviewpeer-review

Abstract / Description of output

Nuclear RNA-binding proteins can record pre-mRNA processing events in the structure of messenger ribonucleoprotein particles (mRNPs). During initial rounds of translation, the mature mRNP structure is established and is monitored by mRNA surveillance systems. Competition for the cap structure links translation and subsequent mRNA degradation, which may also involve multiple deadenylases.

Original languageEnglish
Pages (from-to)320-325
Number of pages6
JournalCurrent opinion in cell biology
Volume13
Issue number3
Publication statusPublished - Jun 2001

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