Multiple origins of Tibetan Y chromosomes

Y Qian; B Qian; B Su; J Yu; Y Ke; Z Chu; L Shi; D Lu; J Chu; L Jin

Multiple origins of Tibetan Y chromosomes

Y Qian, B Qian, B Su, J Yu, Y Ke, Z Chu, L Shi, D Lu, J Chu, L Jin

School of Regeneration and Repair

Research output: Contribution to journal › Article › peer-review

Abstract

The genetic origin of Tibetans was investigated using Y chromosome markers. A total of three populations were studied, two from central Tibet speaking central Tibetan and one from Yunnan speaking Kham. Two dominant paternal lineages (>80%) were identified in all three populations with one possibly from central Asia (YAP+) and the other from east Asia (M122C). We conclude that Tibetan Y chromosomes may have been derived from two different gene pools, given the virtual absence of M122C in central Asia and YAP+ in east Asia, with drift an unlikely mechanism accounting for these observations.

Original language	English
Pages (from-to)	453-4
Number of pages	2
Journal	Human Genetics
Volume	106
Issue number	4
Publication status	Published - Apr 2000

Keywords / Materials (for Non-textual outputs)

Alu Elements
Asia, Central
Asian Continental Ancestry Group
Biological Evolution
China
Emigration and Immigration
Fathers
Gene Pool
Genetic Markers
Haplotypes
Humans
Tibet
Y Chromosome

Cite this

@article{383bab75318a434083029d18862f461a,

title = "Multiple origins of Tibetan Y chromosomes",

abstract = "The genetic origin of Tibetans was investigated using Y chromosome markers. A total of three populations were studied, two from central Tibet speaking central Tibetan and one from Yunnan speaking Kham. Two dominant paternal lineages (>80\%) were identified in all three populations with one possibly from central Asia (YAP+) and the other from east Asia (M122C). We conclude that Tibetan Y chromosomes may have been derived from two different gene pools, given the virtual absence of M122C in central Asia and YAP+ in east Asia, with drift an unlikely mechanism accounting for these observations.",

keywords = "Alu Elements, Asia, Central, Asian Continental Ancestry Group, Biological Evolution, China, Emigration and Immigration, Fathers, Gene Pool, Genetic Markers, Haplotypes, Humans, Tibet, Y Chromosome",

author = "Y Qian and B Qian and B Su and J Yu and Y Ke and Z Chu and L Shi and D Lu and J Chu and L Jin",

year = "2000",

month = apr,

language = "English",

volume = "106",

pages = "453--4",

journal = "Human Genetics",

issn = "0340-6717",

publisher = "Springer",

number = "4",

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TY - JOUR

T1 - Multiple origins of Tibetan Y chromosomes

AU - Qian, Y

AU - Qian, B

AU - Su, B

AU - Yu, J

AU - Ke, Y

AU - Chu, Z

AU - Shi, L

AU - Lu, D

AU - Chu, J

AU - Jin, L

PY - 2000/4

Y1 - 2000/4

N2 - The genetic origin of Tibetans was investigated using Y chromosome markers. A total of three populations were studied, two from central Tibet speaking central Tibetan and one from Yunnan speaking Kham. Two dominant paternal lineages (>80%) were identified in all three populations with one possibly from central Asia (YAP+) and the other from east Asia (M122C). We conclude that Tibetan Y chromosomes may have been derived from two different gene pools, given the virtual absence of M122C in central Asia and YAP+ in east Asia, with drift an unlikely mechanism accounting for these observations.

AB - The genetic origin of Tibetans was investigated using Y chromosome markers. A total of three populations were studied, two from central Tibet speaking central Tibetan and one from Yunnan speaking Kham. Two dominant paternal lineages (>80%) were identified in all three populations with one possibly from central Asia (YAP+) and the other from east Asia (M122C). We conclude that Tibetan Y chromosomes may have been derived from two different gene pools, given the virtual absence of M122C in central Asia and YAP+ in east Asia, with drift an unlikely mechanism accounting for these observations.

KW - Alu Elements

KW - Asia, Central

KW - Asian Continental Ancestry Group

KW - Biological Evolution

KW - China

KW - Emigration and Immigration

KW - Fathers

KW - Gene Pool

KW - Genetic Markers

KW - Haplotypes

KW - Humans

KW - Tibet

KW - Y Chromosome

M3 - Article

C2 - 10830914

SN - 0340-6717

VL - 106

SP - 453

EP - 454

JO - Human Genetics

JF - Human Genetics

IS - 4

ER -

Multiple origins of Tibetan Y chromosomes

Abstract

Keywords / Materials (for Non-textual outputs)

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