Multiplex cancer cell detection by SERS nanotags with cyanine and triphenylmethine Raman reporters

Kaustabh Kumar Maiti; Animesh Samanta; Marc Vendrell; Kiat-Seng Soh; Malini Olivo; Young-Tae Chang

doi:10.1039/c0cc05265e

Multiplex cancer cell detection by SERS nanotags with cyanine and triphenylmethine Raman reporters

Kaustabh Kumar Maiti, Animesh Samanta, Marc Vendrell, Kiat-Seng Soh, Malini Olivo, Young-Tae Chang^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

SERS nanotags have been prepared to accomplish the multiplex detection of cancer cells. Herein we evaluated the adequacy of lipoic acid-containing cyanine derivatives (Cy3LA and Cy5LA) to function as multiplex partners with a triphenylmethine Raman reporter (B2LA) under a single excitation wavelength. SERS experiments enabled the multiplex recognition of two different cancer cells with antibody-conjugated nanotags that were derivatized with optimized cyanine and triphenylmethine reporters.

Original language	English
Pages (from-to)	3514-3516
Number of pages	3
Journal	Chemical Communications
Volume	47
Issue number	12
DOIs	https://doi.org/10.1039/c0cc05265e
Publication status	Published - 2011

Keywords / Materials (for Non-textual outputs)

CY5 DERIVATIVES
SPECTROSCOPY
RECEPTORS
DYES

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10.1039/c0cc05265e

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title = "Multiplex cancer cell detection by SERS nanotags with cyanine and triphenylmethine Raman reporters",

abstract = "SERS nanotags have been prepared to accomplish the multiplex detection of cancer cells. Herein we evaluated the adequacy of lipoic acid-containing cyanine derivatives (Cy3LA and Cy5LA) to function as multiplex partners with a triphenylmethine Raman reporter (B2LA) under a single excitation wavelength. SERS experiments enabled the multiplex recognition of two different cancer cells with antibody-conjugated nanotags that were derivatized with optimized cyanine and triphenylmethine reporters.",

keywords = "CY5 DERIVATIVES, SPECTROSCOPY, RECEPTORS, DYES",

author = "Maiti, {Kaustabh Kumar} and Animesh Samanta and Marc Vendrell and Kiat-Seng Soh and Malini Olivo and Young-Tae Chang",

year = "2011",

doi = "10.1039/c0cc05265e",

language = "English",

volume = "47",

pages = "3514--3516",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

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TY - JOUR

T1 - Multiplex cancer cell detection by SERS nanotags with cyanine and triphenylmethine Raman reporters

AU - Maiti, Kaustabh Kumar

AU - Samanta, Animesh

AU - Vendrell, Marc

AU - Soh, Kiat-Seng

AU - Olivo, Malini

AU - Chang, Young-Tae

PY - 2011

Y1 - 2011

N2 - SERS nanotags have been prepared to accomplish the multiplex detection of cancer cells. Herein we evaluated the adequacy of lipoic acid-containing cyanine derivatives (Cy3LA and Cy5LA) to function as multiplex partners with a triphenylmethine Raman reporter (B2LA) under a single excitation wavelength. SERS experiments enabled the multiplex recognition of two different cancer cells with antibody-conjugated nanotags that were derivatized with optimized cyanine and triphenylmethine reporters.

AB - SERS nanotags have been prepared to accomplish the multiplex detection of cancer cells. Herein we evaluated the adequacy of lipoic acid-containing cyanine derivatives (Cy3LA and Cy5LA) to function as multiplex partners with a triphenylmethine Raman reporter (B2LA) under a single excitation wavelength. SERS experiments enabled the multiplex recognition of two different cancer cells with antibody-conjugated nanotags that were derivatized with optimized cyanine and triphenylmethine reporters.

KW - CY5 DERIVATIVES

KW - SPECTROSCOPY

KW - RECEPTORS

KW - DYES

U2 - 10.1039/c0cc05265e

DO - 10.1039/c0cc05265e

M3 - Article

SN - 1359-7345

VL - 47

SP - 3514

EP - 3516

JO - Chemical Communications

JF - Chemical Communications

IS - 12

ER -

Multiplex cancer cell detection by SERS nanotags with cyanine and triphenylmethine Raman reporters

Abstract / Description of output

Keywords / Materials (for Non-textual outputs)

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