Multiplex cancer cell detection by SERS nanotags with cyanine and triphenylmethine Raman reporters

Kaustabh Kumar Maiti, Animesh Samanta, Marc Vendrell, Kiat-Seng Soh, Malini Olivo, Young-Tae Chang

Research output: Contribution to journalArticlepeer-review

Abstract

SERS nanotags have been prepared to accomplish the multiplex detection of cancer cells. Herein we evaluated the adequacy of lipoic acid-containing cyanine derivatives (Cy3LA and Cy5LA) to function as multiplex partners with a triphenylmethine Raman reporter (B2LA) under a single excitation wavelength. SERS experiments enabled the multiplex recognition of two different cancer cells with antibody-conjugated nanotags that were derivatized with optimized cyanine and triphenylmethine reporters.

Original languageEnglish
Pages (from-to)3514-3516
Number of pages3
JournalChemical Communications
Volume47
Issue number12
DOIs
Publication statusPublished - 2011

Keywords

  • CY5 DERIVATIVES
  • SPECTROSCOPY
  • RECEPTORS
  • DYES

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