Mutation analysis of three genes encoding novel LKB1-interacting proteins, BRG1, STRADα, and MO25α, in Peutz–Jeghers syndrome

P Alhopuro, P Katajisto, R Lehtonen, S K Ylisaukko-oja, L Näätsaari, A Karhu, A M Westerman, J H P Wilson, F W M De Rooij, T Vogel, G Moeslein, I P Tomlinson, L A Aaltonen, T P Mäkelä, V Launonen

Research output: Contribution to journalArticlepeer-review

Abstract

Mutations in LKB1 lead to Peutz–Jeghers syndrome (PJS). However, only a subset of PJS patients harbours LKB1 mutations. We performed a mutation analysis of three genes encoding novel LKB1-interacting proteins, BRG1, STRADα, and MO25α, in 28 LKB1-negative PJS patients. No disease-causing mutations were detected in the studied genes in PJS patients from different European populations.
Original languageEnglish
Pages (from-to)1126-1129
JournalBritish Journal of Cancer
Volume92
Issue number6
DOIs
Publication statusPublished - 28 Mar 2005

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