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Abstract / Description of output
We report on a pilot study of dynamic lung electrical impedance tomography (EIT) at the University of Manchester. Low-noise EIT data at 100 frames per second were obtained from healthy male subjects during controlled breathing, followed by magnetic resonance imaging (MRI) subsequently used for spatial validation of the EIT reconstruction. The torso surface in the MR image and electrode positions obtained using MRI fiducial markers informed the construction of a 3D finite element model extruded along the caudal-distal axis of the subject. Small changes in the boundary that occur during respiration were accounted for by incorporating the sensitivity with respect to boundary shape into a robust temporal difference reconstruction algorithm. EIT and MRI images were co-registered using the open source medical imaging software, 3D Slicer. A quantitative comparison of quality of different EIT reconstructions was achieved through calculation of the mutual information with a lung-segmented MR image. EIT reconstructions using a linear shape correction algorithm reduced boundary image artefacts, yielding better contrast of the lungs, and had 10% greater mutual information compared with a standard linear EIT reconstruction.
Original language | English |
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Pages (from-to) | 863-879 |
Number of pages | 17 |
Journal | Physiological Measurement |
Volume | 35 |
Issue number | 5 |
Early online date | 8 Apr 2014 |
DOIs | |
Publication status | Published - 31 May 2014 |
Keywords / Materials (for Non-textual outputs)
- 3D lung EIT
- MRI
- mutual information
- image co-registration
- ELECTRICAL-IMPEDANCE TOMOGRAPHY
- BOUNDARY SHAPE
- HIGH-SPEED
- VENTILATION
- RECONSTRUCTION
- CONDUCTIVITY
- RESISTIVITY
- REGISTRATION
- UNIQUENESS
- PERFUSION
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Hugh Mccann
- School of Engineering - Visitor: Official Visitor
Person: Affiliated Independent Researcher