Myocardial blood-oxygen-level-dependent magnetic resonance imaging with balanced steady-state free precession imaging approaches

Rohan Dharmakumar*, Sotirios A. Tsaftaris, Debiao Li

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

The current state of myocardial Blood-Oxygen-Level-Dependent (BOLD) MRI with balanced steady-state free precession (SSFP) approaches is reviewed. Initial studies forming the basis for SSFP-based detection of oxygenation changes beginning with whole blood studies, progressing through controlled studies that consider microcirculatory changes in oxygenation in skeletal muscle and kidney, culminating in basic myocardial studies are outlined. The theoretical basis to observe signal changes and the mechanisms that facilitate such observations are elucidated. Methods to overcome limitations in sensitivity are described.

Original languageEnglish
Pages (from-to)31-38
Number of pages8
JournalOpen Medical Imaging Journal
Volume6
Issue numberSPEC.ISS.1
DOIs
Publication statusPublished - 2012

Keywords / Materials (for Non-textual outputs)

  • Blood
  • BOLD
  • Cardiac
  • Ischemic heart disease
  • Oxygen
  • SSFP

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