n-3 Fatty acid erythrocyte membrane content, APOE varepsilon4, and cognitive variation: An observational follow-up study in late adulthood

Lawrence J Whalley; Ian J Deary; John Starr; Klaus W Wahle; Kellie A Rance; Victoria J Bourne; Helen C Fox

n-3 Fatty acid erythrocyte membrane content, APOE varepsilon4, and cognitive variation: An observational follow-up study in late adulthood

Lawrence J Whalley, Ian J Deary, John Starr, Klaus W Wahle, Kellie A Rance, Victoria J Bourne, Helen C Fox

Research output: Contribution to journal › Article › peer-review

Abstract

Evidence for an inverse relation between dietary intake of n-3 polyunsaturated fatty acids (PUFAs) and age-related cognitive decline is inconsistent. This inconsistency may arise because the relation is present only in the absence of the apolipoprotein E epsilon4 (APOE epsilon4) allele.

Original language	English
Pages (from-to)	449-54
Number of pages	6
Journal	The American Journal of Clinical Nutrition (AJCN)
Volume	87
Issue number	2
Publication status	Published - 2008

Keywords

aged
aging
Apolipoprotein E4
cognition
erythrocyte membrane
fatty acids, Omega-3
female
follow-up studies
humans
male
middle aged

Cite this

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title = "n-3 Fatty acid erythrocyte membrane content, APOE varepsilon4, and cognitive variation: An observational follow-up study in late adulthood",

abstract = "Evidence for an inverse relation between dietary intake of n-3 polyunsaturated fatty acids (PUFAs) and age-related cognitive decline is inconsistent. This inconsistency may arise because the relation is present only in the absence of the apolipoprotein E epsilon4 (APOE epsilon4) allele.",

keywords = "aged, aging, Apolipoprotein E4, cognition, erythrocyte membrane, fatty acids, Omega-3, female, follow-up studies, humans, male, middle aged",

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year = "2008",

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journal = "The American Journal of Clinical Nutrition (AJCN)",

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T1 - n-3 Fatty acid erythrocyte membrane content, APOE varepsilon4, and cognitive variation

T2 - An observational follow-up study in late adulthood

AU - Whalley, Lawrence J

AU - Deary, Ian J

AU - Starr, John

AU - Wahle, Klaus W

AU - Rance, Kellie A

AU - Bourne, Victoria J

AU - Fox, Helen C

PY - 2008

Y1 - 2008

N2 - Evidence for an inverse relation between dietary intake of n-3 polyunsaturated fatty acids (PUFAs) and age-related cognitive decline is inconsistent. This inconsistency may arise because the relation is present only in the absence of the apolipoprotein E epsilon4 (APOE epsilon4) allele.

AB - Evidence for an inverse relation between dietary intake of n-3 polyunsaturated fatty acids (PUFAs) and age-related cognitive decline is inconsistent. This inconsistency may arise because the relation is present only in the absence of the apolipoprotein E epsilon4 (APOE epsilon4) allele.

KW - aged

KW - aging

KW - Apolipoprotein E4

KW - cognition

KW - erythrocyte membrane

KW - fatty acids, Omega-3

KW - female

KW - follow-up studies

KW - humans

KW - male

KW - middle aged

M3 - Article

C2 - 18258638

VL - 87

SP - 449

EP - 454

JO - The American Journal of Clinical Nutrition (AJCN)

JF - The American Journal of Clinical Nutrition (AJCN)

SN - 0002-9165

IS - 2

ER -

n-3 Fatty acid erythrocyte membrane content, APOE varepsilon4, and cognitive variation: An observational follow-up study in late adulthood

Abstract

Keywords

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