n-3 Fatty acid erythrocyte membrane content, APOE varepsilon4, and cognitive variation: An observational follow-up study in late adulthood

Lawrence J Whalley, Ian J Deary, John Starr, Klaus W Wahle, Kellie A Rance, Victoria J Bourne, Helen C Fox

Research output: Contribution to journalArticlepeer-review

Abstract

Evidence for an inverse relation between dietary intake of n-3 polyunsaturated fatty acids (PUFAs) and age-related cognitive decline is inconsistent. This inconsistency may arise because the relation is present only in the absence of the apolipoprotein E epsilon4 (APOE epsilon4) allele.
Original languageEnglish
Pages (from-to)449-54
Number of pages6
JournalAmerican Journal of Clinical Nutrition
Volume87
Issue number2
Publication statusPublished - 2008

Keywords

  • aged
  • aging
  • Apolipoprotein E4
  • cognition
  • erythrocyte membrane
  • fatty acids, Omega-3
  • female
  • follow-up studies
  • humans
  • male
  • middle aged

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