N-[Chloro(dimethylamino)methylene]-N-methylmethanaminium chloride (TMUCI Cl), the reagent of choice for the solid-phase synthesis of anilides

M Vendrell, R Ventura, A Ewenson, M Royo*, F Albericio

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

An effective solid-phase preparation of anilides from supported carboxylic acids is described by their activation as the corresponding acid chlorides with TMUCI Cl. (c) 2005 Elsevier Ltd. All rights reserved.

Original languageEnglish
Pages (from-to)5383-5386
Number of pages4
JournalTetrahedron Letters
Volume46
Issue number32
DOIs
Publication statusPublished - 8 Aug 2005

Keywords / Materials (for Non-textual outputs)

  • amide formation
  • combinatorial chemistry
  • coupling reagents
  • p-nitroanilide
  • peptide synthesis
  • PEPTIDE
  • ACIDS

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