Natural cytokine antagonists and endogenous antiendotoxin core antibodies in sepsis syndrome. The Sepsis Intervention Group

A S Goldie, K C Fearon, J A Ross, G R Barclay, R E Jackson, I S Grant, G Ramsay, A S Blyth, J C Howie

Research output: Contribution to journalArticlepeer-review

Abstract

To assess the value of measuring circulating concentrations of mediators (endotoxin, tumor necrosis factor-alpha [TNF-alpha], interleukin-1 beta [IL-1 beta], and interleukin-6[IL-6]) and their endogenous antagonists (antiendotoxin core antibody [EndoCAb], interleukin-1 receptor antagonist [IL-1ra], and soluble TNF receptors [sTNF-R]) in predicting mortality and organ failure in sepsis syndrome.
Original languageEnglish
Pages (from-to)172-7
Number of pages6
JournalJournal of the American Medical Association
Volume274
Issue number2
Publication statusPublished - 1995

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