Abstract / Description of output
Drug Induced Liver Injury (DILI) has a high incidence rate across the globe, particularly in mainland China where its estimated incidence in the general population can reach over 23 cases per 100,000. MicroRNA-122 (miR-122) has been proposed as a sensitive DILI marker although no commercial applications are available yet. Here we report a novel platform combining a microfluidic cartridge extraction and Electro-Impedance Spectroscopy (EIS), and demonstrate a proof-of-concept point-of-care diagnostic test of DILI on clinical patient samples.
Original language | English |
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Title of host publication | MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
Publisher | Chemical and Biological Microsystems Society |
Pages | 564-565 |
Number of pages | 2 |
ISBN (Electronic) | 9781733419048 |
Publication status | Published - 2022 |
Event | 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2022 - Hybrid, Hangzhou, China Duration: 23 Oct 2022 → 27 Oct 2022 |
Conference
Conference | 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2022 |
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Country/Territory | China |
City | Hybrid, Hangzhou |
Period | 23/10/22 → 27/10/22 |
Keywords / Materials (for Non-textual outputs)
- Blood
- Drug-Induced Liver Injury
- MicroRNA
- miR-122