Neoadjuvant chemotherapy for carcinoma of the oesophagus and oesophago-gastric junction: a six-year experience

Brian P Halliday; Richard Je Skipworth; Lucy Wall; Hamish A Phillips; Graeme W Couper; Andrew C de Beaux; Simon Paterson-Brown

doi:10.1186/1477-7800-4-24

Neoadjuvant chemotherapy for carcinoma of the oesophagus and oesophago-gastric junction: a six-year experience

Brian P Halliday, Richard Je Skipworth, Lucy Wall, Hamish A Phillips, Graeme W Couper, Andrew C de Beaux, Simon Paterson-Brown

School of Regeneration and Repair

Research output: Contribution to journal › Article › peer-review

Abstract

Oesophageal cancer is a major clinical problem with a generally poor prognosis. As a result there has been interest in combining surgery with neoadjuvant chemotherapy to try and improve outcomes, although the current evidence for benefit is inconsistent. We aimed to compare, in a non-randomised study, the post-operative complication rate and short and long-term survival of patients who underwent surgical resection for carcinoma of the oesophagus and types I and II carcinoma of the oesophago-gastric junction with or without neo-adjuvant chemotherapy.

Original language	English
Pages (from-to)	24
Journal	International seminars in surgical oncology : ISSO
Volume	4
DOIs	https://doi.org/10.1186/1477-7800-4-24
Publication status	Published - 2007

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title = "Neoadjuvant chemotherapy for carcinoma of the oesophagus and oesophago-gastric junction: a six-year experience",

abstract = "Oesophageal cancer is a major clinical problem with a generally poor prognosis. As a result there has been interest in combining surgery with neoadjuvant chemotherapy to try and improve outcomes, although the current evidence for benefit is inconsistent. We aimed to compare, in a non-randomised study, the post-operative complication rate and short and long-term survival of patients who underwent surgical resection for carcinoma of the oesophagus and types I and II carcinoma of the oesophago-gastric junction with or without neo-adjuvant chemotherapy.",

author = "Halliday, \{Brian P\} and Skipworth, \{Richard Je\} and Lucy Wall and Phillips, \{Hamish A\} and Couper, \{Graeme W\} and \{de Beaux\}, \{Andrew C\} and Simon Paterson-Brown",

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T1 - Neoadjuvant chemotherapy for carcinoma of the oesophagus and oesophago-gastric junction

T2 - a six-year experience

AU - Halliday, Brian P

AU - Skipworth, Richard Je

AU - Wall, Lucy

AU - Phillips, Hamish A

AU - Couper, Graeme W

AU - de Beaux, Andrew C

AU - Paterson-Brown, Simon

PY - 2007

Y1 - 2007

N2 - Oesophageal cancer is a major clinical problem with a generally poor prognosis. As a result there has been interest in combining surgery with neoadjuvant chemotherapy to try and improve outcomes, although the current evidence for benefit is inconsistent. We aimed to compare, in a non-randomised study, the post-operative complication rate and short and long-term survival of patients who underwent surgical resection for carcinoma of the oesophagus and types I and II carcinoma of the oesophago-gastric junction with or without neo-adjuvant chemotherapy.

AB - Oesophageal cancer is a major clinical problem with a generally poor prognosis. As a result there has been interest in combining surgery with neoadjuvant chemotherapy to try and improve outcomes, although the current evidence for benefit is inconsistent. We aimed to compare, in a non-randomised study, the post-operative complication rate and short and long-term survival of patients who underwent surgical resection for carcinoma of the oesophagus and types I and II carcinoma of the oesophago-gastric junction with or without neo-adjuvant chemotherapy.

U2 - 10.1186/1477-7800-4-24

DO - 10.1186/1477-7800-4-24

M3 - Article

C2 - 17937823

SN - 1477-7800

VL - 4

SP - 24

JO - International seminars in surgical oncology : ISSO

JF - International seminars in surgical oncology : ISSO

ER -

Neoadjuvant chemotherapy for carcinoma of the oesophagus and oesophago-gastric junction: a six-year experience

Abstract

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